M. Rohm

NF-kappaB and JNK pathways mediate metabolic adaptation upon ESCRT-I deficiency

This study shows that ESCRT-I deficiency leads to metabolic reprogramming via NF-kappaB and JNK pathways, causing increased glycolysis and lipid accumulation.

Macroscopic label-free biomedical imaging withshortwave infrared Raman scattering

This paper introduces a shortwave infrared Raman imaging technique that enables label-free, high-contrast visualization of tissue composition and pathology without contrast agents.

Housing temperature dictates the systemic and tissue specific molecular responses to cancer in mice

This study shows that housing temperature affects molecular and systemic responses to cancer in mice, influencing metabolic adaptations and cytokine levels.

Chronic intermittent fasting impairs β-cell maturation and function in adolescent mice

This study shows chronic intermittent fasting impairs β-cell maturation and function in adolescent mice, but not in adults, with similar patterns observed in human type 1 diabetes.

The myocyte Nfe2l1-ubiquitin-proteasome system controls muscle fiber type and obesity-induced insulin resistance

This study shows that Nfe2l1 regulates skeletal muscle proteostasis and function, with its loss causing muscle fiber type switching and insulin resistance in high-fat diet conditions.