M. Schulz

CRISPR-inhibition screen for lncRNAs linked to melanoma growth and metastasis

The paper identifies lncRNAs involved in melanoma growth and metastasis using CRISPR-inhibition screens and validates their functional roles.

Tripartite interactions of PKA catalytic subunit and C-terminal domains of cardiac Ca2+ channel modulate its β-adrenergic regulation

This study identifies direct interactions between PKA catalytic subunit and C-terminal domains of cardiac CaV1.2 channels, revealing their role in modulating β-adrenergic regulation.

Functional expression of a Mo-dependent formate dehydrogenase in Escherichia coli under aerobic conditions

The paper reports the functional expression of a Mo-dependent formate dehydrogenase in E. coli under aerobic conditions, showing growth on formate as sole energy source and identifying mutations in a formate transporter gene as key to adaptation.

Habitat quality, not patch isolation, drives distribution and abundance of two light-demanding butterflies in fragmented coppice landscapes

The Open Field test as a tool for behavior analysis in pigs - is a standardization of setup necessary? A systematic review.

This review examines Open Field test setups in pig studies, finding high variability in parameters and calling for standardization to improve consistency and comparability.

Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis

The paper shows that blocking CSF1R in brain metastases initially reduces tumor growth but is ineffective in established tumors due to compensatory macrophage activation, which is overcome by combining CSF1R and STAT5 inhibition.

Differential impact of plant secondary metabolites on the soil microbiota

The paper examines how three plant metabolites affect soil bacterial communities, finding distinct impacts on taxa abundance and diversity.