N. C. Wu

Structural study of a cross-reactive SARS antibody reveals a conserved epitope on the SARS-CoV-2 receptor-binding domain.

This study characterizes a monoclonal antibody against the N-terminal domain of PfCSP, finding it has high affinity but lacks functional inhibitory activity against sporozoites.

The paper evaluates genetic barriers to resistance against broadly neutralizing antibodies targeting the stem region of influenza H3 and H1 hemagglutinins, finding H3 has lower resistance barriers.

GLAnCE is a hydrogel platform that enables real-time observation of CAF-tumour cell interactions at the tumour-stroma interface, revealing interface-specific invasion and EMT gene induction.

The paper experimentally measures the effects of all single amino-acid mutations in H3N2 influenza HA on viral growth and shows their correlation with evolutionary success in natural lineages.