Author

N. Hua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Zhou· 2 shared G. Zheng· 2 shared X. Zhang· 2 shared A. Sobh· 1 shared C. Hann· 1 shared D. Lv· 1 shared D. Thummuri· 1 shared F. J. Kaye· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

D. Zhou

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibits small-cell lung cancer growth without causing on-target toxicities in mice

S. KHAN, P. Kellish, N. Connis, D. Thummuri, J. Wiegand, P. Zhang, X. Zhang, V. Budamagunta, N. Hua, Y. Yang, U. De, L. Jin, W. Zhang, G. Zheng, R. Hromas, , D. Zhou

bioRxiv · Sep 12, 2022Cancer Biology

Piperlongumine (PL) conjugates induce targeted protein degradation

J. Pei, Y. Xiao, X. Liu, W. Hu, A. Sobh, Y. Yuan, S. Zhou, N. Hua, S. G. Mackintosh, X. Zhang, K. B. Basso, M. Kamat, Q. Yang, J. D. Licht, G. Zheng, , D. Lv

The paper identifies piperlongumine as a covalent E3 ligase recruiter that, when conjugated with CDK9 inhibitors, induces targeted protein degradation of CDK9 and EML4-ALK fusion oncoprotein.

bioRxiv · Jan 21, 2022Cancer Biology