Author

D. Lv

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Sobh· 1 shared A. Yang· 1 shared C. Lv· 1 shared C. Wang· 1 shared C. Yang· 1 shared D. Zhou· 1 shared G. Long· 1 shared G. Zheng· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. Sobh

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LncCE: Landscape of Cellular-Elevated LncRNAs in Single Cells Across Normal and Cancer Tissues

K. Xu, Y. Liu, C. Lv, Y. Luo, J. Shi, H. Zou, W. Zhou, D. Lv, C. Yang, Y. Li, J. Xu

LncCE identifies and characterizes cellular-elevated lncRNAs across normal and cancer tissues using single-cell RNA sequencing data, providing expression patterns and clinical associations.

bioRxiv · May 17, 2024Cancer Biology

Piperlongumine (PL) conjugates induce targeted protein degradation

J. Pei, Y. Xiao, X. Liu, W. Hu, A. Sobh, Y. Yuan, S. Zhou, N. Hua, S. G. Mackintosh, X. Zhang, K. B. Basso, M. Kamat, Q. Yang, J. D. Licht, G. Zheng, , D. Lv

The paper identifies piperlongumine as a covalent E3 ligase recruiter that, when conjugated with CDK9 inhibitors, induces targeted protein degradation of CDK9 and EML4-ALK fusion oncoprotein.

bioRxiv · Jan 21, 2022Cancer Biology

Genetic determinants of COVID-19 drug efficacy revealed by genome-wide CRISPR screens

W. Jiang, A. Yang, J. Ma, D. Lv, M. Liu, L. Xu, C. Wang, Z. He, S. Chen, J. Zhao, S. Chen, Q. Jiang, Y. Chu, L. Shan, Z. Zhou, , H. Jiang

This study identifies genetic determinants of COVID-19 drug efficacy using genome-wide CRISPR screens, revealing genes involved in drug metabolism and immunosuppressive effects.

bioRxiv · Oct 26, 2020 · PreprintPharmacology & Toxicology