N. Nishimura

Sexual dimorphism in melanocyte stem cell behavior reveals combinational therapeutic strategies for cutaneous repigmentation

The paper identifies sexual dimorphism in melanocyte stem cell behavior and proposes combinational therapy for vitiligo repigmentation.

A multivariate network analysis of ring- and diffuse-porous tree xylem vasculature segmented by convolutional neural networks

This paper analyzes xylem vessel networks in six tree species using convolutional neural networks and network metrics to relate structural properties to hydraulic vulnerability and drought resistance.

Engineered retrovirus-like nanocarriers for messenger RNA delivery into neurons

This paper develops engineered retrovirus-like nanocarriers for efficient mRNA delivery into neurons by modifying extracellular vesicles with Arc protein capsids and RNA elements.

Genetically Engineered Strains for Combinatorial Cardiovascular Optobiology

The paper introduces 21 genetically engineered mouse lines for combinatorial optogenetic studies in cardiovascular biology, enabling biallelic combination of effectors and sensors in multiple cell types.

In vivo multiphoton microscopy of cardiomyocyte calcium dynamics in the beating mouse heart

The paper uses in vivo multiphoton microscopy to study cardiomyocyte calcium dynamics in a beating mouse heart, capturing 3D data of tissue structure and GCaMP6f activity during cardiac and respiratory cycles.

Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging

This study shows that intestinal crypts rapidly recover from focal damage through coordinated stem cell motion, which is impaired by aging.