C. Seo

Targeted Kinase Degradation via the KLHDC2 Ubiquitin E3 Ligase

This study demonstrates the use of KLHDC2 as a substrate adaptor for targeted protein degradation using peptide-based bivalent compounds.

Engineered retrovirus-like nanocarriers for messenger RNA delivery into neurons

This paper develops engineered retrovirus-like nanocarriers for efficient mRNA delivery into neurons by modifying extracellular vesicles with Arc protein capsids and RNA elements.

TCF7L1 and TCF7 differentially regulate specific mouse ES cell genes in response to GSK-3 inhibition

This study shows TCF7L1 and TCF7 have distinct chromatin occupancy patterns in mouse ES cells, with TCF7L1 binding more genes and showing target-specific modulation by GSK-3 inhibition.

Endogenous BioID elucidates TCF7L1 interactome modulation upon GSK-3 inhibition in mouse ESCs

The paper uses BioID to study TCF7L1 interactome changes in mouse ESCs with GSK-3 inhibition, identifying new interactors and showing increased detection with reduced BirA*-TCF7L1 levels.

Altitudinal range-size distribution of breeding birds and environmental factors for the determination of species richness: An empirical test of altitudinal Rapoports rule and rescue effect on a local scale

This study tests altitudinal Rapoports rule and rescue effect by analyzing species range-size distribution and environmental factors, finding support for Rapoports rule and climatic hypothesis but not ambient energy hypothesis.

Effective soil extraction method for cultivating previously uncultured soil bacteria

The paper introduces a new soil extract medium (ISEM) that isolates previously uncultured bacteria, with 49% of isolates being previously uncultured and 55% representing new taxonomic candidates.