O. Schmidt

Microbial aerotrophy enables continuous primary production in diverse cave ecosystems

This study identifies aerotrophy as a primary energy source in caves, revealing microbial use of atmospheric trace gases for continuous primary production.

Revealing the Arabidopsis AtGRP7 mRNA binding proteome by specific enhanced RNA interactome capture

The paper identifies proteins interacting with the AtGRP7 mRNA in Arabidopsis using enhanced RNA interactome capture, revealing ALBA proteins as binders.

The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi

This study identifies the Dsc ubiquitin ligase complex as a quality control mechanism at the Golgi that degrades orphaned proteins by assessing transmembrane domain hydrophobicity.

The structure of the Orm2-containing serine palmitoyltransferase complex reveals distinct inhibitory potentials of yeast Orm proteins.

The paper determines the cryo-EM structure of the SPT-Orm2 complex and shows Orm2 has higher inhibitory potential than Orm1, despite similar structures.

A metabolically controlled contact site between lipid droplets and vacuoles

This study identifies Ldo16/45 as proteins forming a tether-complex with Vac8 to create vCLIP contact sites between lipid droplets and vacuoles, linking LD biogenesis and breakdown.

Utilizing a nanobody recruitment approach for assessing serine palmitoyltransferase activity in ER sub-compartments of yeast.

The paper develops a nanobody recruitment system to measure SPT activity in yeast ER sub-compartments, identifying two distinct active SPT pools.

Global monitoring of soil animal communities using a common methodology

The paper introduces a global collaborative network to standardize soil animal community monitoring and food web analysis across diverse ecosystems.

In vivo imaging of swimming micromotors using hybrid high-frequency ultrasound and photoacoustic imaging

This paper develops a hybrid imaging system combining high-frequency ultrasound and photoacoustic imaging to track magnetically driven micromotors in vivo and ex vivo.

Complementary α-arrestin - Rsp5 ubiquitin ligase complexes control selective nutrient transporter endocytosis in response to amino acid availability

The paper identifies complementary α-arrestin-Rsp5 complexes that regulate selective endocytosis of nutrient transporters based on amino acid availability.

Multiple roles for the ESCRT machinery in maintaining plasma membrane homeostasis

This study investigates the role of ESCRT machinery in plasma membrane homeostasis using budding yeast, revealing its involvement in membrane tension regulation and sphingolipid metabolism through calcineurin/TORC2 signaling.