Author

P. Finneran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Hartzler· 1 shared A. W. Smith· 1 shared B. P. Brown· 1 shared C. M. Lovly· 1 shared C. Wilson· 1 shared D. Kern· 1 shared D. Swaney· 1 shared D. Theobald· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. L. Hartzler

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2 papers

Recent·Most cited

Allele-specific activation, enzyme kinetics, and inhibitor sensitivities of EGFR exon 19 deletion mutations in lung cancer

B. P. Brown, Y. Zhang, S. Kim, P. Finneran, Y. Yan, Z. Du, J. Kim, A. L. Hartzler, M. L. LeNoue-Newton, A. W. Smith, J. Meiler, C. M. Lovly

The paper identifies allele-specific functional differences among EGFR exon 19 deletion variants, showing how sequence and structure motifs affect oncogenic activity, dimerization, and TKI sensitivity.

bioRxiv · Mar 16, 2022Cancer Biology

Bimodal evolution of Src and Abl kinase substrate specificity revealed using mammalian cell extract as substrate pool

P. Finneran, M. Soucheray, C. Wilson, R. Otten, V. Buosi, N. J. Krogan, D. Swaney, D. Theobald, D. Kern

This study reveals the bimodal evolution of Src and Abl kinase substrate specificity using mammalian cell extract as a substrate pool, showing divergent evolutionary paths leading to specific and promiscuous enzymes.

bioRxiv · Aug 12, 2020 · PreprintBiochemistry