Using NAMs to characterize chemical bioactivity at the transcriptomic, proteomic and phosphoproteomic levels
Y. Li, Z. zhang, S. Jiang, F. Xu, L. Tulum, K. Li, S. Liu, S. Li, L. Chang, M. Liddell, F. Tu, X. Gu, P. L. Carmichael, A. White, S. Peng, , P. Xu
This paper integrates multi-omic data to characterize chemical bioactivity at transcriptomic, proteomic, and phosphoproteomic levels, showing how early phosphoproteomic changes drive downstream effects.
bioRxiv · May 18, 2022 · PreprintPharmacology & Toxicology