Mutation divergence over space in tumour expansion
H. Li, F. Tu, L. Deng, Z. Yang, X. Fu, L. Wang, D. GU, B. Werner, W. Huang
This study quantifies how mutation divergence varies with sampling distance and tumour expansion modes using simulations, showing that mutation rate inference is less accurate with smaller sampling sizes and slower expansion.
Journal of The Royal Society Interface · Nov 1, 2023Peer-reviewedCancer Biology