Author

P. Lai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Alimonti· 1 shared A. Cavalli· 1 shared A. Liu· 1 shared A. R. Angel· 1 shared A. Rinaldi· 1 shared B. Cali· 1 shared E. Pasquini· 1 shared G. Attanasio· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. Alimonti

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mitochondrial DNA released by senescent cells triggers immunosuppression in cancer

P. Lai, L. Liu, N. Bancaro, M. Troiani, B. Cali, J. Chen, P. K. Singh, R. A. Arzola, G. Attanasio, N. Pernigoni, E. Pasquini, S. Mosole, A. Rinaldi, J. Sgrignani, Y. Li, , A. Alimonti

This study shows that mtDNA released by senescent cells triggers immunosuppression via PMN-MDSCs, and inhibiting this pathway enhances therapy-induced senescence in cancer.

bioRxiv · Aug 6, 2023 · PreprintCell Biology

Mecp2 Fine-tunes Quiescence Exit by Targeting Nuclear Receptors

J. Yang, S. Zou, Z. Qiu, M. Lai, Q. Long, H. Chen, P. Lai, S. Zhang, Z. Rao, X. Xie, Y. Gong, A. Liu, M. Li, X. Bai

This study shows Mecp2 negatively regulates quiescence exit by activating metabolic genes and repressing proliferation genes, with nuclear receptors Rara and Nr1h3 playing a key role.

bioRxiv · Jul 24, 2023Cell Biology