Y. Gui

OsHMA3 overexpression works more efficiently in generating low-Cd rice grain than OsNramp5 knockout mutation

This study compares OsNramp5 knockout and OsHMA3 overexpression in reducing grain cadmium in rice, finding OsHMA3 overexpression more effective without impairing manganese uptake.

Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis

This study identifies Calponin 2's role in kidney fibrosis by linking cellular mechanics to metabolic reprogramming via fatty acid oxidation regulation.

Mitogen-activated protein kinases associated sites of tobacco REPRESSION OF SHOOT GROWTH regulates its localization in plant cells

This study identifies MAPK-associated phosphorylation sites in RSG that regulate its subcellular localization and function in tobacco.

Beneficial Effects of Celastrol on Immune Balance by Modulating Gut Microbiota in Dextran Sodium Sulfate-Induced Ulcerative Colitis

This study shows that Celastrol reduces colitis by modulating gut microbiota, improving immune balance, and increasing metabolites like pyruvate and adenosine.

Transcription factor-like 5 is a potential DNA/RNA-binding protein essential for maintaining male fertility in mice.Running title: Tcfl5 is haploinsufficient in vivo

This study identifies Tcfl5 as a testis-specific protein essential for male fertility, showing that heterozygous mice are infertile and exhibit abnormalities in spermatids and spermatozoa.

The pleiotropic effects of the MNK1/2-eIF4E axis support immune suppression and metastasis in a model of postpartum breast cancer.

This study shows that the MNK1/2-eIF4E axis promotes immune suppression and metastasis in postpartum breast cancer by affecting both tumor and non-tumor cells.

Modern human origins: multiregional evolution of autosomes and East Asia origin of Y and mtDNA

The paper challenges the Recent Out of Africa model by proposing multiregional evolution of autosomes and East Asian origin of modern Y and mtDNA through hybridization with archaic humans.