P. Trieu-Cuot

This study profiles the transcriptome of human colonic cells exposed to SGG, showing it induces stronger transcriptional changes in cancerous HT29 cells than in normal FHC cells, with significant ER stress and UPR activation.

This paper characterizes gallocin A, a two-peptide bacteriocin from SGG, showing it requires intramolecular disulfide bonds for activity and that its immunity peptide shares structural features with the toxin.

This study shows that SGG UCN34 promotes colon cancer by activating multiple cancer-related signaling pathways through proteomic and phosphoproteomic analyses in mice and human tumors.

This study shows that prophages in Staphylococcus aureus modulate lipid incorporation into bacterial membranes, affecting antibiotic resistance and infection dynamics.

This paper shows that (p)ppGpp and malonyl-CoA modulate S. aureus adaptation to FASII antibiotics, and that combining a (p)ppGpp inducer with an anti-FASII drug blocks bacterial outgrowth.

This study characterizes the CovR regulatory network in Group B Streptococcus, showing its role in virulence gene regulation and strain-specific adaptations.

This paper identifies a 4-component regulatory system in Streptococcus gallolyticus that controls gallocin production through activator and anti-activator proteins.

This paper shows that heterogeneous Pil3 pilus expression in Streptococcus gallolyticus enables translocation across intestinal epithelial barriers.