Author

P. Yao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 5 Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:mouse· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Organism:E. coli· 2

Frequent Co-Authors

J. Wu· 6 shared K. C. V. Subbaiah· 4 shared F. Jiang· 3 shared W. H. W. Tang· 3 shared C. Yan· 2 shared J. Hollinger· 2 shared O. Hedaya· 2 shared A. M. Padilla· 1 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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6 shared papersPathology

J. Wu

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Cardiomyocyte-specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy

J. Wu, J. Hollinger, E. Bonanno, F. Jiang, P. Yao

This study shows that loss of EPRS1 in cardiomyocytes causes dilated cardiomyopathy and heart failure, with altered protein homeostasis and metabolic pathways.

bioRxiv · Sep 19, 2023 · PreprintPathology

Spatiotemporal development of growth and death zones in expanding bacterial colonies driven by emergent nutrient dynamics

H. Kannan, P. Sun, T. Caglar, P. Yao, B. R. Taylor, K. Sahu, D. Ge, M. Mori, M. Warren, D. Kleinfeld, J. Dong, B. Li, T. Hwa

This study shows that bacterial colony expansion is driven by mechanical constraints and nutrient gradients, with cell death occurring in a distinct zone due to glucose depletion and anaerobiosis.

bioRxiv · Aug 27, 2023 · PreprintMicrobiology

Expression and purification of the mitochondrial transmembrane protein FAM210A in Escherichia coli

J. Hollinger, J. Wu, K. M. Awayda, M. R. O'Connell, P. Yao

This study develops a method to purify human FAM210A, a mitochondrial transmembrane protein, using E. coli and validates its interaction with EF-Tu.

bioRxiv · May 27, 2023 · PreprintBiochemistry

FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis

J. Wu, K. C. V. Subbaiah, O. Hedaya, S. Chen, J. Munger, W. H. W. Tang, C. Yan, P. Yao

This study identifies FAM210A as a regulator of mitochondrial translation and cardiac mitochondrial homeostasis, showing its deficiency leads to heart failure and its overexpression rescues cardiac function in ischemic heart disease.

bioRxiv · May 20, 2023Pathology

FAM114A1 Influences Cardiac Fibrosis by Regulating Angiotensin II Signaling in Cardiac Fibroblasts

K. C. V. Subbaiah, J. Wu, W. W. Tang, P. Yao

This study identifies FAM114A1 as a regulator of cardiac fibrosis by modulating Ang II signaling in cardiac fibroblasts, showing its role in fibrosis and potential as a therapeutic target.

bioRxiv · Feb 20, 2021 · PreprintPathology

High variation in immune responses and parasite phenotypes in naturally acquired Trypanosoma cruzi infection in a captive non-human primate breeding colony in Texas, USA

A. M. Padilla, P. Yao, T. Landry, G. M. Cooley, I. Ribeiro, S. Mahaney, J. L. VandeBerg, R. L. Tarleton

The paper investigates immune responses and parasite phenotypes in naturally infected cynomolgus macaques, revealing diverse parasite genetic types and immune profiles despite uniform housing conditions.

bioRxiv · Jan 22, 2021Microbiology

MicroRNA-574 Regulates FAM210A Expression and Influences Pathological Cardiac Remodeling

J. Wu, K. C. V. Subbaiah, F. Jiang, O. Hedaya, A. Mohan, T. Yang, K. Welle, S. Ghaemmaghami, W. H. W. Tang, E. Small, C. Yan, P. Yao

This study identifies miR-574 as a regulator of FAM210A, which influences mitochondrial protein expression and cardiac remodeling in heart failure.

bioRxiv · Jan 9, 2020Pathology

EPRS Regulates Proline-rich Pro-fibrotic Protein Synthesis during Cardiac Fibrosis

J. Wu, K. C. V. Subbaiah, L. H. Xie, F. Jiang, D. Mickelsen, J. R. Myers, W. H. W. Tang, P. Yao

This study identifies EPRS as a key regulator of proline-rich pro-fibrotic gene translation in cardiac fibrosis, showing its role in promoting fibrosis and identifying potential therapeutic targets.

bioRxiv · Sep 20, 2019Pathology