Author

R. Bohat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

W. Peng· 3 shared A. Guerrero· 2 shared C. Xu· 2 shared N. A. Egan· 2 shared N. Zheng· 2 shared R. Jaffery· 2 shared X. Chen· 2 shared A. Leekha· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

W. Peng

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Author profile →

3 papers

Recent·Most cited

LRRK2 G2019S mutation suppresses differentiation of Th9 and Treg cells via JAK/STAT3

N. Zheng, R. Jaffery, A. Guerrero, J. Hou, Y. Pan, F. Zhou, S. Chen, C. Xu, N. A. Egan, R. Bohat, K. Chen, M. A. Schwarzschild, X. Chen, W. Peng

This study shows that the LRRK2 G2019S mutation impairs Th9 and Treg cell differentiation while enhancing Th2 differentiation through JAK/STAT3 signaling in T cells.

bioRxiv · Feb 28, 2024 · PreprintImmunology

FASlpr gene dosage tunes the extent of lymphoproliferation and T cell differentiation in lupus

R. Bohat, X. Liang, Y. Chen, C. Xu, N. Zheng, A. Guerrero, R. Jaffery, N. A. Egan, A. Robles, M. J. Hicks, Y. Du, X. Chen, C. Mohan, W. Peng

This study shows that FASlpr gene dosage affects lymphoproliferation and T cell differentiation in lupus models, with heterozygous Faslpr leading to increased autoantibodies and Th1 cell skewing.

bioRxiv · Nov 1, 2023Immunology

Engineering non-cytotoxic delivery of proteins by T cells via fusion to NPC2

A. Saeedi, I. N. Bandey, A. Leekha, M. Fathi, A. Rezvan, M. J. Montalvo, K.-L. Wu, R. Bohat, W. Peng, N. Varadarajan

This study demonstrates that fusing proteins to NPC2 enables non-cytotoxic protein delivery by T cells through the perforin pathway.

bioRxiv · Sep 24, 2022 · PreprintImmunology