Author

K.-l. Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

C. Yu· 2 shared H. Xiao· 2 shared L. Wu· 2 shared W. Zhang· 2 shared X. Zhang· 2 shared Y. Chen· 2 shared Z. Tian· 2 shared Z. Xu· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

C. Yu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Engineering non-cytotoxic delivery of proteins by T cells via fusion to NPC2

A. Saeedi, I. N. Bandey, A. Leekha, M. Fathi, A. Rezvan, M. J. Montalvo, K.-L. Wu, R. Bohat, W. Peng, N. Varadarajan

This study demonstrates that fusing proteins to NPC2 enables non-cytotoxic protein delivery by T cells through the perforin pathway.

bioRxiv · Sep 24, 2022 · PreprintImmunology

Bone-Specific Enhancement of Antibody Therapy for Breast Cancer Metastasis to Bone

Z. Tian, C. Yu, W. Zhang, K.-l. Wu, R. Gupta, Z. Xu, L. Wu, Y. Chen, X. Zhang, H. Xiao

This paper enhances antibody therapy for breast cancer bone metastasis by engineering antibodies with bone-homing peptides, improving their bone tumor targeting and therapeutic efficacy.

bioRxiv · Aug 31, 2021Bioengineering

Harnessing the Power of Antibodies to Fight Bone Metastasis

Z. Tian, L. Wu, C. Yu, Y. Chen, Z. Xu, I. Bado, A. Loredo, L. Wang, H. Wang, K.-l. Wu, W. Zhang, X. Zhang, H. Xiao

This paper develops a bone-targeting antibody using bisphosphonate conjugation and demonstrates its enhanced efficacy against bone metastases in xenograft models.

bioRxiv · Feb 19, 2021Cancer Biology