Author

R. Ying

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:chicken / avian· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Liang· 1 shared A. Norris· 1 shared B. D. Grant· 1 shared B. Liu· 1 shared C. McManus· 1 shared F. Hu· 1 shared F. Huang· 1 shared F. Yu· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. Liang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mutagenesis and structural modeling implicate RME-8 IWN domains as conformational control points

A. Norris, C. McManus, R. Ying, S. Wang, B. D. Grant

The paper identifies IWN domains in RME-8 as conformational control points that regulate DNAJ domain exposure and function through interactions with SNX-1.

PLOS Genetics · Oct 24, 2022Peer-reviewedCell Biology

Glycopeptide antibiotic teicoplanin inhibits cell entry of SARS-CoV-2 by suppressing the proteolytic activity of cathepsin L

F. Yu, T. Pan, F. Huang, R. Ying, J. Liu, H. Fan, J. Zhang, W. Liu, Y. Lin, Y. Yuan, T. Yang, R. Li, X. Zhang, X. Lv, Q. Chen, , X. Ma

This paper shows that teicoplanin inhibits SARS-CoV-2 cell entry by blocking cathepsin L proteolytic activity, effective against multiple variants with IC50 values of 2.038 M and 2.116 M.

Frontiers in Microbiology · Apr 28, 2022Peer-reviewedMicrobiology

A chicken IgY can efficiently inhibit the entry and replication of SARS-CoV-2 by targeting the ACE2 binding domain in vitro

W. Jingchen, L. Yunfei, R. Ying, Z. Xuanyu, H. Songqing, W. Shuwen, X. Qing

This paper demonstrates that a chicken-derived IgY antibody can inhibit SARS-CoV-2 entry and replication in vitro with high efficacy, outperforming remdesivir.

bioRxiv · Feb 16, 2021 · PreprintImmunology