Author

S. Tirier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Jauch· 1 shared A. Korshunov· 1 shared A. Rademacher· 1 shared A. S. Rifaioglu· 1 shared B. Schoell· 1 shared B. Statz· 1 shared C. Conrad· 1 shared C. Dietz· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Jauch

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2 papers

Recent·Most cited

Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage

D. R. Ghasemi, K. Okonechnikov, A. Rademacher, S. Tirier, K. K. Maass, H. Schumacher, J. Sundheimer, B. Statz, A. S. Rifaioglu, K. Bauer, S. Schumacher, M. Bortolomeazzi, F. Giangaspero, K. J. Ernst, J. Saez-Rodriguez, , K. W. Pajtler

The paper uses single-cell transcriptomics to show how two compartments in medulloblastoma are connected through a migrating precursor stage, revealing spatial and developmental links between proliferating and differentiated tumor cells.

Nature Communications · Jan 8, 2024Peer-reviewedCancer Biology

Induced aneuploidy disrupts MCF10A acini formation and CCND1 expression

M. Waschow, Q. Wang, P. Saary, C. Klein, S. Aschenbrenner, K. Jechow, L. Maier, S. Tirier, B. Schoell, I. Chudoba, C. Dietz, D. Dreidax, A. Jauch, M. Sprick, C. Herrmann, , C. Conrad

This study shows that induced aneuploidy disrupts MCF10A acini formation and upregulates CCND1 expression through altered promoter-enhancer interactions.

bioRxiv · Dec 15, 2019 · PreprintCancer Biology