MicrobiologybioRxiv
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant
L. Yurkovetskiy, X. Wang, K. E. Pascal…·J. Luban
This study shows the D614G SARS-CoV-2 spike protein variant is more infectious but has reduced ACE2 affinity and altered trimer conformation, affecting viral entry and antibody neutralization.
DOI 10.1016/j.cell.2020.09.032