Author

S. Goodwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

E. Hodges· 2 shared K. Chang· 2 shared M. Kramer· 2 shared O. Klingbeil· 2 shared W. R. McCombie· 2 shared Y. Wei· 2 shared Z. Yang· 2 shared A. Myers· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

E. Hodges

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Intratumoral heterogeneity and clonal evolution induced by HPV integration

K. Akagi, D. E. Symer, M. Mahmoud, B. Jiang, S. Goodwin, D. Wangsa, Z. Li, W. Xiao, J. D. Dunn, T. Ried, K. R. Coombes, F. J. Sedlazeck, M. L. Gillison

This study identifies heterocateny as a structural variation caused by HPV integration, promoting intratumoral heterogeneity and clonal evolution in oropharyngeal cancers.

bioRxiv · Aug 11, 2022Cancer Biology

Candidate effector proteins from the maize tar spot pathogen Phyllachora maydis localize to diverse plant cell compartments

M. Helm, R. Singh, R. Hiles, N. Jaiswal, A. Myers, A. S. Iyer-Pascuzzi, S. Goodwin

The paper identifies subcellular localization of effector proteins from the maize pathogen Phyllachora maydis using fluorescent tagging and microscopy.

bioRxiv · May 24, 2022Plant Biology

In vivo genetic screen identifies a SLC5A3-dependent myo-inositol auxotrophy in acute myeloid leukemia

Y. Wei, S. Iyer, S. Costa, Z. Yang, M. Kramer, E. Adelman, O. Klingbeil, O. Demerdash, S. Polyanskaya, K. Chang, S. Goodwin, E. Hodges, W. R. McCombie, M. Figueroa, C. Vakoc

The paper identifies SLC5A3-dependent myo-inositol auxotrophy in AML through genetic screening and shows synthetic lethality between ISYNA1 and SLC5A3.

bioRxiv · Dec 22, 2020 · PreprintCancer Biology

Transcriptional silencing of ALDH2 in acute myeloid leukemia confers a dependency on Fanconi anemia proteins

Z. Yang, Y. Wei, X. S. Wu, S. V. Iyer, M. Jung, E. R. Adelman, O. Klingbeil, M. Kramer, O. E. Demerdash, K. Chang, S. Goodwin, E. Hodges, W. R. McCombie, M. E. Figueroa, A. Smogorzewska, C. R. Vakoc

This study identifies ALDH2 transcriptional silencing in AML as a dependency on FA proteins, suggesting FA pathway targeting as a therapeutic strategy.

bioRxiv · Oct 23, 2020Cancer Biology