Author

S. Kwak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

A. Toor· 1 shared C. A. McHugh· 1 shared D. Barker· 1 shared D. Howland· 1 shared H. Keshishian· 1 shared H. Kim· 1 shared H. Lee· 1 shared H. Specht· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. Toor

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation

R. M. Bragg, S. R. Coffey, J. P. Cantle, S. Hu, S. Singh, S. R. W. Legg, C. A. McHugh, A. Toor, S. O. Zeitlin, S. Kwak, D. Howland, T. F. Vogt, S. P. Monga, J. B. Carroll

This study shows that reducing huntingtin in liver cells leads to metabolic changes, altered cell adhesion, and disrupted liver zonation patterns in mice.

bioRxiv · Jun 24, 2023 · PreprintCell Biology

Huntingtin turnover: Modulation of huntingtin degradation by cAMP-dependent protein kinase A (PKA) phosphorylation of C-HEAT domain Ser2550

Y. Lee, H. Kim, D. Barker, R. Vijayvargia, R. S. Atwal, H. Specht, H. Keshishian, S. A. Carr, R. Lee, S. Kwak, K.-g. Hyun, J. Loupe, M. E. MacDonald, J.-J. Song, I. Seong

The paper identifies phospho-sites in huntingtin, showing PKA phosphorylation of Ser2550 in the C-HEAT domain accelerates its degradation.

bioRxiv · May 4, 2022 · PreprintBiochemistry

Differential risk of incident cancer in patients with heart failure: A nationwide population-based cohort study

S. Kwak, S. Kwon, S.-Y. Lee, S. Yang, H.-J. Lee, H. Lee, J.-B. Park, K. Han, Y.-J. Kim, H.-K. Kim

This study finds that patients with heart failure have a higher risk of developing cancer compared to the general population, with increased risk observed across multiple cancer types.

bioRxiv · Jan 10, 2020Cancer Biology