Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Y. Lee, H. Kim, D. Barker, R. Vijayvargia, R. S. Atwal, H. Specht, H. Keshishian, S. A. Carr, R. Lee, S. Kwak, K.-g. Hyun, J. Loupe, M. E. MacDonald, J.-J. Song, I. Seong
The paper identifies phospho-sites in huntingtin, showing PKA phosphorylation of Ser2550 in the C-HEAT domain accelerates its degradation.
bioRxiv · May 4, 2022 · PreprintBiochemistry
A. G. Specht, S. L. Kurtz, K. L. Elkins, H. Specht, G. Beamer
This study shows BCG vaccination of Diversity Outbred mice increases IgG reactive to SARS-CoV-2 spike protein compared to unvaccinated mice and C57BL/6J mice.
bioRxiv · Apr 18, 2022 · PreprintImmunology
R. G. Huffman, A. Leduc, C. Wichmann, M. di Gioia, F. Borriello, H. Specht, J. Derks, S. Khan, L. Khoury, E. Emmott, A. A. Petelski, D. H. Perlman, J. Cox, I. Zanoni, N. Slavov
The paper introduces pSCoPE, a single-cell proteomics method that improves sensitivity, completeness, and depth, enabling analysis of protein variation in macrophages.
bioRxiv · Mar 16, 2022Immunology
A. A. Petelski, E. Emmott, A. Leduc, R. G. Huffman, H. Specht, D. H. Perlman, N. Slavov
The paper introduces SCoPE2, a multiplexed single-cell proteomics method that enables quantitative analysis of over 1,000 proteins per cell using standard equipment.
bioRxiv · Mar 12, 2021Bioengineering
H. Keshishian, E. R. McDonald, R. Melanson, D. A. Porter, F. Mundth, K. Krug, L. Wallace, D. Forestier, B. Rabasha, S. E. Marlow, J. Jane-Valbuena, E. Todres, H. Specht, J. Golji, E. Kuhn, , S. A. Carr
The paper introduces SigPath, a mass spectrometry assay that quantifies 284 phosphosites across 200 phosphoproteins, revealing new insights into phospho-signaling in cancer models and human tumors.
bioRxiv · Dec 8, 2020Cancer Biology