S. Maurya

Coupling between acid-sensing ion channel 1a and the monocarboxylate transporter family shapes cellular pH response

The paper identifies a functional interaction between ASIC1a and MCT1 that modulates proton sensitivity and desensitization, showing its role in glioblastoma cell survival and mouse lifespan.

mTOR signaling regulates aberrant epithelial cell proliferative and migratory behaviors characteristic of airway mucous metaplasia in asthma

This study shows mTOR signaling drives aberrant epithelial behaviors in asthma, including proliferation and migration, and its inhibition reduces mucous metaplasia features.

Ligand-Dependent Mechanisms of C-C Chemokine Receptor 5 (CCR5) Trafficking Revealed by APEX2 Proximity Labeling Proteomics

This study uses APEX2 proximity labeling and mass spectrometry to uncover ligand-dependent CCR5 trafficking mechanisms, revealing distinct internalization and degradation pathways.

Proteome allocation is linked to transcriptional regulation through a modularized transcriptome

The paper investigates modularization of bacterial transcriptomes and proteomes to uncover relationships between their compositions and regulatory mechanisms.

Conformational flexibility is a key determinant of the lytic activity of the pore forming protein, Cytolysin A

This study shows that conformational flexibility in the β-tongue and N-terminus regions of ClyA is essential for its lytic activity and membrane-mediated conformational transition.

Faunistic study on the freshwater ciliates from Delhi, India

The paper documents freshwater ciliate diversity in Delhi, India, identifying 55 species across multiple classes and finding highest diversity at Okhla bird sanctuary.