Author

S. O'Dell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:non-human primate· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:structural biology· 1

Frequent Co-Authors

L. Wang· 4 shared N. A. Doria-Rose· 4 shared S. D. Schmidt· 4 shared A. R. Henry· 3 shared W. Shi· 3 shared A. Dodson· 2 shared A. Pegu· 2 shared A. Van Ry· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersImmunology

L. Wang

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates

M. Gagne, B. J. Flynn, S. F. Andrew, D. R. Flebbe, A. Mychalowych, E. Lamb, M. E. Davis-Gardner, M. R. Burnett, L. A. Serebryannyy, B. C. Lin, L. Pessaint, J.-P. M. Todd, Z. E. Ziff, E. Maule, R. Carroll, , M Suthar

This study shows that mucosal adenoviral-vectored vaccines provide durable protection against XBB.1.16 infection in nonhuman primates, outperforming intramuscular boosting in reducing virus replication in both upper and lower airways.

bioRxiv · Nov 6, 2023 · PreprintImmunology

Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant

S. M. Scheaffer, D. Lee, B. Whitener, B. Ying, K. Wu, H. Jani, P. Martin, N. J. Amato, L. E. Avena, D. M. Berrueta, S. D. Schmidt, S. O'Dell, A. Nasir, G.-Y. Chuang, G. Stewart-Jones, , M. S. Diamond

This study evaluates bivalent SARS-CoV-2 mRNA vaccines and finds they induce broader neutralizing antibodies and better protection against BA.5 Omicron compared to monovalent vaccines.

bioRxiv · Sep 12, 2022 · PreprintMicrobiology

Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones

N. S. Lima, M. Musayev, T. S. Johnston, D. A. Wagner, A. R. Henry, L. Wang, E. S. Yang, Y. Zhang, K. Birungi, W. P. Black, S. O'Dell, S. D. Schmidt, D. Moon, C. G. Lorang, B. Zhao, , P. D. Kwong

The paper examines antibody responses to SARS-CoV-2 variants, finding convergent epitope specificities, V gene usage, and public B cell clones across different variants.

bioRxiv · Mar 28, 2022Immunology

Protection against SARS-CoV-2 Beta Variant in mRNA-1273 Boosted Nonhuman Primates

K. S. Corbett, M. Gagne, D. Wagner, S. O'Connell, S. R. Narpala, D. R. Flebbe, S. F. Andrew, R. L. Davis, B. Flynn, T. S. Johnston, C. Stringham, L. Lai, D. Valentin, A. Van Ry, Z. Flinchbaugh, , A Pekosz

mRNA-1273 boosted nonhuman primates show increased neutralizing antibody responses and protection against SARS-CoV-2 beta variant infection.

bioRxiv · Aug 11, 2021 · PreprintImmunology

Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants

A. Pegu, S. E. O'Connell, S. D. Schmidt, S. O'Dell, C. A. Talana, L. Lai, J. Albert, E. Anderson, H. Bennett, K. Corbett, B. Flach, L. Jackson, B. Leav, J. E. Ledgerwood, C. J. Luke, , N. A. Doria-Rose

This study assesses the durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants over seven months, finding persistent but reduced binding and functional responses.

bioRxiv · May 13, 2021 · PreprintImmunology

Structurally related but genetically unrelated antibody lineages converge on an immunodominantHIV-1 Env neutralizing determinant following trimer immunization

S. Aljedani, T. J. Liban, K. Tran, G. Phad, S. Singh, V. Dubrovskaya, P. Pushparaj, P. Martinez-Murillo, J. Rodarte, A. Mileant, V. Mangala, R. Kinzelman, S. O'Dell, J. R. Mascola, K. K. Lee, , M. Pancera

The paper analyzes monoclonal antibodies from vaccinated non-human primates to identify a conserved immunodominant epitope in HIV-1 Env and how different lineages target it for potent neutralization.

bioRxiv · Apr 9, 2021Biochemistry