Author

S. Z. Josefowicz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Assay:ChIP-seq· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

A. Murison· 2 shared A. W. Daman· 2 shared J. E. Dick· 2 shared J.-G. Cheong· 2 shared S. Z. Xie· 2 shared A. Armache· 1 shared A. G. Aguilar-Navarro· 1 shared A. G. X. Zeng· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

A. Murison

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mechanisms of Epigenomic and Functional Convergence Between Glucocorticoid and IL4-Driven Macrophage Programming

D. K. Deochand, M. Dacic, M. J. Bale, A. W. Daman, S. Z. Josefowicz, D. Oliver, Y. Chinenov, I. Rogatsky

This study identifies shared and distinct mechanisms of macrophage programming by IL4 and glucocorticoids, revealing GRIP1's role in integrating their effects on transcription and function.

bioRxiv · Feb 16, 2024Immunology

Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection.

A. Lercher, J.-G. Cheong, C. Jiang, H.-H. Hoffmann, A. W. Ashbrook, Y. S. Yin, C. Quirk, E. J. DeGrace, L. Chiriboga, B. R. Rosenberg, S. Z. Josefowicz, C. M. Rice

This study shows that SARS-CoV-2 infection primes alveolar macrophages for enhanced antiviral responses against influenza A virus through epigenetic changes in IFN-I pathways.

bioRxiv · Nov 24, 2023 · PreprintImmunology

Identification of a human hematopoietic stem cell subset that retains memory of inflammatory stress

A. G. X. Zeng, M. S. Nagree, N. A. Jakobsen, S. Shah, A. Murison, J.-G. Cheong, S. Turkalj, I. Lim, L. Jin, J. Araujo, A. G. Aguilar-Navarro, D. Parris, J. McLeod, H. Kim, H. S. Lee, , S. Z. Xie

The paper identifies a human HSC subset with inflammatory memory that accumulates with age and clonal hematopoiesis, potentially increasing cancer and infection risks.

bioRxiv · Sep 11, 2023 · PreprintCell Biology

Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing

T. Itkin, S. Houghton, R. Schreiner, Y. Lin, C. Badwe, V. Voisin, A. Murison, N. Seyedhassantehrani, K. B. Kaufmann, L. Garcia-Prat, G. T. Booth, F. Geng, Y. Liu, J. M. Gomez-Salinero, J.-H. Shieh, , S. Rafii

The paper identifies Fli-1's role in regulating HSC activation during regenerative hematopoiesis by enabling niche signaling and functional recovery.

bioRxiv · Mar 27, 2023 · PreprintCell Biology

Phosphorylation of the ancestral histone variant H3.3 amplifies stimulation-induced transcription

A. Armache, S. Yang, L. E. Robbins, C. Durmaz, A. W. Daman, J. Q. Jeong, A. Martinez de Paz, A. Ravishankar, T. Arslan, S. Lin, T. Panchenko, B. A. Garcia, S. Hake, H. Li, C. D. Allis, S. Z. Josefowicz

The paper identifies phosphorylation of H3.3S31 in response to pathogen sensing in macrophages and shows its role in recruiting SETD2 to enhance transcription of inflammatory genes.

bioRxiv · Oct 17, 2019 · PreprintBiochemistry