T. Jung

Age pigment lipofuscin causes oxidative stress, lysosomal dysfunction, and pyroptotic cell death

This study isolates authentic lipofuscin from cardiac tissue and shows it induces oxidative stress, lysosomal dysfunction, and pyroptotic cell death in fibroblasts.

Oxic microbial electrosynthesis can be more energy efficient for biomass production than knallgas or photosynthesis based processes

This study demonstrates that oxic microbial electrosynthesis can achieve higher energy efficiency for biomass production than traditional gas fermentation or photosynthesis-based processes.

Structural basis of recognition and destabilization of histone H2B ubiquitinated nucleosome by DOT1L histone H3 Lys79 methyltransferase

The paper presents cryo-EM structures of DOT1L with nucleosomes and shows H2B ubiquitination enhances DOT1L's non-catalytic nucleosome destabilization function.

Integrative structure investigation on the architecture of human Importin4_histone H3/H4_Asf1a complex and its histone H3 tail binding

This study investigates the structure of the Importin4_histone H3/H4_Asf1a complex and identifies key interactions between Importin4 and the histone H3 tail.