J. Yoon

CODANIN-1 sequesters ASF1 by using a histone H3 mimic helix to regulate the histone supply

This study determines the structure of the CODANIN-1_ASF1 complex, revealing how CODANIN-1 inhibits ASF1-mediated histone supply by sequestering ASF1 in the cytoplasm.

Glomerular Elastic Modulus and Gene Expression PatternsDefine Two Phases of Alport Nephropathy

This study identifies early glomerular changes and gene expression patterns in Alport syndrome, showing ER stress and four genes as key drivers of disease before proteinuria, and highlights potential therapeutic targets.

DFNA5-mediated pyroptosis is a driver for venetoclax and azacytidine synergy in myeloid leukemia

This study shows that DFNA5-mediated pyroptosis contributes to the synergy between venetoclax and azacytidine in myeloid leukemia, beyond apoptosis.

The Immune-Evasive Proline 283 Substitution in Influenza Nucleoprotein Increases Aggregation Propensity Without Altering the Native Structure

The paper investigates how the Pro283 substitution in influenza nucleoprotein affects protein folding and aggregation, revealing it increases aggregation propensity without altering native structure.

SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating Hes5

This study identifies SOX15's role in maintaining pluripotency and promoting neural differentiation by interacting with coactivators and activating Hes5.

Phylogenetic analysis of human parainfluenza type 3 virus strains responsible for the outbreak during the COVID-19 pandemic in Seoul, South Korea

The paper analyzes HPIV3 strains from a Seoul outbreak, finding a new genetic cluster within subcluster C3 with unique amino acid substitutions.

Diverse northern Asian and Jomon-related genetic structure discovered among socially complex Three Kingdoms period Gaya region Koreans

The study reports the first ancient Korean genomes from the Three Kingdoms period, revealing genetic diversity linked to northern Chinese and Japanese Jomon-related ancestry.

Acoustic Force Spectroscopy Reveals Subtle Differences in Cellulose Unbinding Behavior of Carbohydrate-Binding Modules

This paper uses acoustic force spectroscopy to study how carbohydrate-binding modules (CBMs) unbind from nanocellulose surfaces, revealing distinct binding conformations and their impact on cellulolytic activity.

Genotype of Human Papilloma virus in Male Genital Warts In Korean Men and Review of Literature

The paper analyzes HPV types in male genital warts from Korean men and reviews literature, finding HPV6 and 11 are most common, with Gardasil 9 covering >80% of cases.

The Host Cell's Endoplasmic Reticulum Proteostasis Network Profoundly Shapes the Protein Sequence Space Accessible to HIV Envelope

This study shows that upregulating the host ER proteostasis network via the UPR reduces mutational tolerance of HIV Env, with some regions becoming more tolerant, suggesting host proteostasis influences HIV adaptation.

Factors that influence the thymic selection of CD8αα intraepithelial lymphocytes

The paper investigates factors influencing thymic selection of CD8αα intraepithelial lymphocytes, finding that CD8 IEL development requires a higher TCR affinity threshold than negative selection.

Dose assessment in dental cone beam computed tomography: comparison of optically stimulated luminescence dosimetry with the Monte Carlo method

This study compares optically stimulated luminescence dosimetry with Monte Carlo simulation to assess patient dose in dental cone beam computed tomography across different examination modes.

A role for phagocytosis in inducing cell death during thymocyte negative selection

This study shows that phagocytosis enhances negative selection of autoreactive thymocytes by promoting their death, with more efficient elimination when phagocytes also present the negative selecting peptide.

Continuous, Topologically Guided Protein Crystallization Controls Bacterial Surface Layer Self-Assembly

This study shows that protein self-assembly alone can form and maintain bacterial surface layers, guided by surface topology without enzymatic assistance.

Revealing the nanoscale morphology of the primary cilium using super-resolution fluorescence microscopy

This study uses super-resolution microscopy and computational methods to quantify nanoscale morphology changes in primary cilia under different treatments.

Integrative structure investigation on the architecture of human Importin4_histone H3/H4_Asf1a complex and its histone H3 tail binding

This study investigates the structure of the Importin4_histone H3/H4_Asf1a complex and identifies key interactions between Importin4 and the histone H3 tail.

Holographic deep learning for rapid optical screening of anthrax spores

This paper develops a deep learning method using holographic microscopy to rapidly and accurately classify anthrax spores and other pathogens.

Label-free identification of non-activated lymphocytes using three-dimensional refractive index tomography and machine learning

This study identifies non-activated lymphocyte subtypes using label-free refractive index tomography and machine learning with high specificity and sensitivity.