T. Lim

Single-cell and spatial atlas of steatotic liver-related hepatocellular carcinoma

This study characterizes the tumor microenvironment of steatotic liver-related hepatocellular carcinoma using single-cell and spatial transcriptomic analyses, identifying immunosuppressive features and Treg-CAF interactions linked to immunotherapy resistance.

Comparing virtual staining artificial intelligence model performance on same-tissue versus serial-tissue sections based on CD3+ T-cell ground truth

This study compares a virtual staining AI model's performance on same-tissue versus serial-tissue sections using CD3+ T-cell ground truth, finding better performance with same-tissue data.

In vitro broad-spectrum antiviral activity of MIT-001, a mitochondria-targeted reactive oxygen species scavenger, against severe acute respiratory syndrome coronavirus 2 and multiple zoonotic viruses

This study evaluates MIT-001's antiviral activity against SARS-CoV-2 and zoonotic viruses in vitro, showing inhibition of viral replication and restoration of antioxidant gene expression.

Continuous Fish Muscle Cell Line with Capacity for Myogenic and Adipogenic-like Phenotypes

The paper establishes and characterizes a continuous Atlantic mackerel skeletal muscle cell line with myogenic and adipogenic-like phenotypes.

Maternal immunity and antibodies to dengue promote Zika virus-induced microcephaly in fetuses

The paper shows maternal DENV antibodies enhance ZIKV vertical transmission and cause microcephaly in fetuses via FcRN, linking maternal immunity to severe fetal outcomes.