J. W. Kim

This study evaluates MIT-001's antiviral activity against SARS-CoV-2 and zoonotic viruses in vitro, showing inhibition of viral replication and restoration of antioxidant gene expression.

This study shows that darapladib, an Lp-PLA2 inhibitor, enhances ferroptosis in cancer cells by altering lipid metabolism and synergizes with GPX4 inhibitors to suppress tumor growth.

This study evaluates the antiviral efficacy of remdesivir, molnupiravir, and nirmatrelvir against newly emerged SARS-CoV-2 Omicron subvariants and finds they retain antiviral activity.

This study investigates DLL3's role in Notch signaling and SCLC heterogeneity, finding that high DLL3 levels promote a mixed neuroendocrine and non-neuroendocrine cell population.

This study compares the infectivity of SARS-CoV-2 variants in human alveolar cells, finding Omicron (BA.1) to be 3-5-fold more infectious than other variants at early infection.

This study identifies that the co-deletion of CIC and ERF leads to ETV1 activation, driving prostate cancer progression without fusion events.

This study characterizes the phenotypic and genotypic features of Listeria monocytogenes isolates from Korean ruminant clinical cases, revealing genetic diversity and antimicrobial resistance.

This paper develops a multi-stage MPC strategy to optimize parallel mini-bioreactor operations under parametric uncertainties, improving experimental success rates.

This study identifies two novel paramyxoviruses, PAPV-1 and PAPV-2, from Apodemus agrarius rodents in Korea, revealing distinct genome structures and zoonotic potential.

This study develops human spinal cord-like organoids (hSCOs) to enable quantitative drug screening for neural tube defects.

The paper shows STRIPAK directs PP2A to dephosphorylate MAP4K4, promoting oncogenic transformation via YAP1 activation.

This study models bistable tumour population dynamics to evaluate treatment strategies, finding that periodic treatments outperform static ones and optimal control theory-based treatments are most effective.

This study shows that sialyllactose enhances bacterial clearance in mice and human macrophages through receptor-mediated endocytosis, phagocytosis, and Rac1-mediated reactive oxygen species production.