Author

T. Weil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Conzelmann· 3 shared J. A. Mueller· 3 shared J. Muench· 3 shared R. Gross· 3 shared A. Kleger· 2 shared F. Kirchhoff· 2 shared F. Zech· 2 shared L. Wettstein· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

C. Conzelmann

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structural adaptability and surface activity oftardigrade-inspired peptides

G. Giubertoni, S. Chagri, P. G. Argudo, F. Caporaletti, A. Greco, L. Pradel, A. Pavan, I. M. Ilie, Y. Ren, D. Ng, M. Bonn, T. Weil, S. Woutersen

This paper studies model peptides derived from tardigrade proteins to mimic their structural behavior under desiccation, finding they adopt helical structures similar to full proteins.

bioRxiv · Oct 27, 2023 · PreprintBiochemistry

Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry

Y. Lin, H. Jung, C. A. Bulman, J. Ng, R. Vinck, C. O'Beirne, M. S. Moser, N. Tricoche, R. Peguero, R. W. Li, J. F. Urban, P. Le Pape, F. Pagniez, M. Moretto, T. Weil, , G. Gasser

Simple derivatives of the well-known antifungal drug fluconazole were found to be highly effective in vivo against fungal infections and potent against parasitic nematodes causing lymphatic filariasis and soil-transmitted helminths.

bioRxiv · Jun 28, 2023Pharmacology & Toxicology

Antiviral activity of plant juices and green tea against SARS-CoV-2 and influenza virus in vitro

B. Frank, C. Conzelmann, T. Weil, R. Gross, P. Jungke, M. Eggers, J. A. Mueller, J. Muench, U. Kessler

This study evaluates the antiviral effects of plant juices and green tea against SARS-CoV-2 and influenza virus in vitro, finding that chokeberry juice inactivates SARS-CoV-2 and influenza virus, while other products show limited efficacy.

bioRxiv · Oct 30, 2020Microbiology

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition

C. Prelli Bozzo, R. Nchioua, M. Volcic, J. Krueger, S. Heller, C. M. Stuerzel, D. Kmiec, C. Conzelmann, J. A. Mueller, F. Zech, D. Schuetz, L. Koepke, E. Braun, R. Gross, L. Wettstein, , F. Kirchhoff

This study shows that IFITM proteins are required for SARS-CoV-2 infection and can be targeted to inhibit viral entry and replication.

bioRxiv · Aug 18, 2020 · PreprintMicrobiology

Alpha-1 antitrypsin inhibits SARS-CoV-2 infection

L. Wettstein, C. Conzelmann, J. A. Mueller, T. Weil, R. Gross, M. Hirschenberger, A. Seidel, S. Klute, c. Prelli-Bozzo, F. Zech, N. Preising, G. Fois, R. Lochbaum, P. Knaff, V. Mailaender, , J. Muench

The paper identifies 1-antitrypsin as a specific inhibitor of SARS-CoV-2, showing it blocks viral infection of human airway epithelium at physiological concentrations.

bioRxiv · Jul 2, 2020 · PreprintMicrobiology