Author

J.-W. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Organism:human· 2

Frequent Co-Authors

A. Kim· 1 shared A. Voshall· 1 shared B. Lee· 1 shared C. T. Trinh· 1 shared C. Young· 1 shared C.-O. Jeon· 1 shared C.-R. Lee· 1 shared D.-M. Yu· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCell Biology

A. Kim

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Pan-cancer analysis reveals multifaceted roles of retrotransposon-fusion RNAs

B. Lee, J. Park, A. Voshall, E. Maury, Y. Kang, Y. J. Kim, J.-Y. Lee, H.-R. Shim, H.-J. Kim, J.-W. Lee, M.-H. Jung, S.-C. Kim, H. B. K. Chu, D.-W. Kim, M. Kim, , E. A. Lee

The paper identifies cancer-specific transposon-fusion RNAs across 34 cancer types and finds they are associated with tumor suppressors and oncogenes, and can activate T-cells.

bioRxiv · Oct 16, 2023 · PreprintCancer Biology

Divergent LD-transpeptidase-independent effects of peptidoglycan carboxypeptidases on intrinsic ss-lactam and vancomycin resistance

S. H. Park, U. Choi, S.-H. Ryu, H. B. Lee, J.-W. Lee, C.-R. Lee

This study shows that peptidoglycan carboxypeptidases in E. coli and B. subtilis affect vancomycin and β-lactam resistance independently of LD-transpeptidases, with deletion causing β-lactam sensitivity and vancomycin resistance.

bioRxiv · Apr 4, 2022 · PreprintMicrobiology

Central role of Prominin-1 in lipid rafts during liver regeneration

M.-S. Bahn, D.-M. Yu, M. Lee, S.-J. Jo, J.-W. Lee, H. Lee, A. Kim, J.-H. Hong, J.-S. Kim, S.-H. Koo, J.-S. Lee, Y.-G. Ko

This study shows PROM1 is crucial in lipid rafts for liver regeneration by recruiting GP130 and activating the IL6-GP130-STAT3 pathway.

bioRxiv · Jan 20, 2022Cell Biology

Probing Specificities of Alcohol Acyltransferases for Designer Ester Biosynthesis with a High-Throughput Microbial Screening Platform

J.-W. Lee, H. Seo, C. Young, C. T. Trinh

This paper develops a high-throughput microbial screening platform to identify AATs for selective designer ester biosynthesis, demonstrating its effectiveness with specific AAT variants.

bioRxiv · Jun 26, 2021Bioengineering

Heme auxotrophy in abundant aquatic microbial lineages

S. Kim, I. Kang, J.-W. Lee, C.-O. Jeon, S. J. Giovannoni, J.-C. Cho

The paper identifies heme auxotrophy in the acI bacterial lineage and shows it is widespread in uncultivated microbial groups, suggesting heme could enhance microbial culture diversity.

bioRxiv · Jan 11, 2021Microbiology

Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity

L. Cui, S.-Y. Chen, T. Lerbs, J.-W. Lee, P. Domizi, S. Gordon, Y.-h. Kim, G. P. Nolan, P. Betancur, G. Wernig

This study shows JUN activation in fibroblasts drives fibrosis and modulates immunity, with therapeutic potential through targeting IL-6, CD47, and PD-L1.

bioRxiv · Mar 18, 2020Immunology