V. Jimenez

Amikacin potentiator activity of zinc complexed to a pyrithione derivative with enhanced solubility

This paper tests a zinc-pyrithione derivative with improved solubility as an amikacin potentiator against antibiotic-resistant bacteria.

Transcriptional, epigenetic, and functional reprogramming of blood monocytes in non-human primates following chronic alcohol drinking

This study examines how chronic alcohol drinking affects monocytes and macrophages in non-human primates, revealing hyper-inflammatory responses and impaired function.

No evidence of phago-mixotropy in Micromonas polaris, the dominant picophytoplankton species in the Arctic

The study investigates whether Micromonas polaris is phago-mixotrophic and finds no evidence of bacterial ingestion in any strain.

Cerebrospinal fluid (CSF) boosts metabolism and virulence expression factors in Acinetobacter baumannii

This study shows that cerebrospinal fluid (CSF) enhances virulence factor expression and metabolic processes in low-virulence Acinetobacter baumannii strains.

A novel mechanosensitive channel controls osmoregulation, differentiation and infectivity in Trypanosoma cruzi

This study identifies and characterizes TcMscS, a mechanosensitive channel in Trypanosoma cruzi, showing its role in osmoregulation, differentiation, and infectivity.

Restoration of Susceptibility to Amikacin by 8-Hydroxyquinoline Analogs Complexed to Zinc

This study evaluates 8-hydroxyquinoline analogs complexed with zinc to restore amikacin susceptibility in AAC(6)-Ib-producing Acinetobacter baumannii strains.

A Mouse Model Of Binge Alcohol Consumption and Burkholderia Infection

This study shows that binge alcohol consumption increases Burkholderia infection severity by reducing immune function and increasing tissue permeability and bacterial spread.

Identification of a Small Molecule Inhibitor of the Aminoglycoside 6’-N-Acetyltransferase Type Ib [AAC(6’)-Ib] Using Mixture-Based Combinatorial Libraries

The paper identifies a small molecule inhibitor of AAC(6’)-Ib using combinatorial libraries and evaluates its efficacy against antibiotic-resistant bacteria.