Author

W. B. Mair

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. A. Kelley· 2 shared E. J. Cram· 2 shared K. Burkewitz· 2 shared A. Longchamp· 1 shared A. MacInnes· 1 shared C. Haynes· 1 shared C. Statzer· 1 shared C. Y. Ewald· 1 shared

Activity by Year

2020-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

C. A. Kelley

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Author profile →

4 papers

Recent·Most cited

PhysiologybioRxivPreprintNov 2, 2020

ATF-4 and hydrogen sulfide signalling mediate longevity from inhibition of translation or mTORC1

C. Statzer, J. Meng, R. Venz…·C. Y. Ewald

The paper shows that ATF-4 and hydrogen sulfide signaling mediate longevity from translation or mTORC1 inhibition in C. elegans.

DOI 10.1101/2020.11.02.364703

C. elegansexperimental assay

𝕏 PostBluesky

Cell BiologyCytoskeletonPeer-reviewedOct 8, 2020

FLN-1/Filamin is required to anchor the actomyosin cytoskeleton and for global organization of sub-cellular organelles in a contractile tissue

C. A. Kelley, O. Triplett, S. Mallick…·E. J. Cram

This study shows that FLN-1/filamin anchors actomyosin fibers and maintains sub-cellular organelle organization in C. elegans spermatheca.

DOI 10.1002/cm.21633

C. elegansimaging

𝕏 PostBluesky

Cell BiologyJournal of Cell BiologyPeer-reviewedApr 7, 2020

Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30

Y. Liu, R. McIntyre, G. Janssens…·R. Houtkooper

This study shows that inhibiting both mitochondrial translation and dynamics in C. elegans synergistically extends lifespan through HLH-30-dependent lysosome biogenesis and autophagy.

DOI 10.1083/jcb.201907067

C. elegansbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivJan 14, 2020

Atf-6 regulates lifespan through ER-mitochondrial calcium homeostasis

K. Burkewitz, S. Dutta, C. A. Kelley…·W. B. Mair

This study shows that Atf-6 extends lifespan in C. elegans by modulating ER-mitochondrial calcium homeostasis and signaling.

DOI 10.1016/j.celrep.2020.108125

C. elegansgenetic perturbation / CRISPR

𝕏 PostBluesky