High-throughput generic single-entity sequencing using droplet microfluidics
G. Wang, L. Zhao, Y. Shi, F. Qu, Y. Ding, W. Liu, C. Liu, G. Luo, M. Li, X. Bai, L. Li, Y.-P. Ho, J. Yu
This paper introduces GSE-Seq, a high-throughput platform for single-entity sequencing that enables long-read profiling of dsDNA and ssDNA from viruses and bacteria, revealing previously overlooked dark matter and phage-host interactions.
bioRxiv · Aug 15, 2023Bioengineering