proteomics

Starve, stress, and mate: Activation of the CCAAT-Binding complex overrides sterility of mating-type heterozygous Candida albicans

The paper identifies the CCAAT-binding complex (CBC) as a key regulator that overrides genetic sterility in Candida albicans by integrating environmental stress signals to enable mating.

Deprivation of dietary fiber promotes low-grade neuroinflammation and anxiety-like behavior in mice

This study shows that depriving mice of fermentable dietary fiber leads to low-grade neuroinflammation and anxiety-like behavior, which are reversed by fiber supplementation.

Genetic Variation in Photosynthetic Maintenance and Post-Chill Recovery for Early Season Maize Plantings

This study evaluates genetic variation in maize's response to chilling stress and recovery, identifying heritable traits linked to cold resilience.

Nutrient-responsive midgut turnover is spatially controlled by serotonin signaling

The paper shows serotonin signaling spatially controls nutrient-responsive midgut turnover in Drosophila by regulating enteroblast maturation and morphological changes through the 5HT7 receptor.

Anionic lipids stabilize etioplast prolamellar bodies and facilitate thylakoid biogenesis during etioplast-to-chloroplast differentiation

This study investigates the role of anionic lipids in etioplast-to-chloroplast differentiation, finding that phosphatidylglycerol is crucial for membrane processes while sulfoquinovosyldiacylglycerol supports chloroplast development under PG limitation.

Podoplanin shapes epidermal morphogenesis and coordinates stem cell and epidermal-dermal responses during inflammatory remodelling

This study identifies podoplanin's role in maintaining epidermal organisation and coordinating stem cell and dermal responses during inflammatory skin remodelling.

Amyloid/RNA Condensates with Germ Granule Characteristics Are Present in Rat Epididymal Spermatozoa and Exhibit Prion-Like Propagation Activity

The paper identifies germ granule-like amyloid/RNA condensates in rat epididymal spermatozoa that exhibit prion-like propagation activity, suggesting a non-Mendelian mechanism for transmitting environmental information to offspring.

CO2-concentrating nanoparticles drive progressive photosynthetic and cell-wall remodelling in Arabidopsis thaliana cells

The paper shows that CO2-concentrating nanoparticles modify photosynthesis and cell wall structure in Arabidopsis cells over time.

Species-specific WNT requirements shape somite morphogenesis in mammalian embryo models

This study compares somitogenesis across human, pig, sheep, and cow stem cell-derived embryo models, revealing species-specific WNT signaling and extracellular matrix requirements for axial segmentation.

Sodium arsenite requires redox sensitization to cause developmental dopaminergic neurotoxicity in Caenorhabditis elegans

This study shows that sodium arsenite requires additional mitochondrial or redox stress to cause dopaminergic neurotoxicity in C. elegans, but not fluoroacetic acid.

cGAS integrates Toll-like receptor signaling in platelets to promote thromboinflammation

This study shows that cGAS integrates TLR signaling in platelets to drive thromboinflammation by sensing mitochondrial DNA.

Application of organic fertilisation such as poultry manure enhanced carbohydrate, fat and vitamin C contents of Huckleberry (Solanum scabrum) more than mineral fertilisation in Buea-Cameroon

This study compares the effects of organic and inorganic fertilizers on huckleberry growth and nutritional content, finding that poultry manure enhances micronutrients more than urea, which boosts yield.

Combined elevated temperature and CO2 alter Wolbachia abundance and host fitness but not cytoplasmic incompatibility in a stored-product pest

This study examines how elevated temperature and CO2 affect Wolbachia abundance and host fitness in a stored-product pest, finding stable cytoplasmic incompatibility despite changes in Wolbachia dynamics.

Circadian multimodal physiological, ocular and behavioural data from a 40-hour forced-desynchrony protocol

The paper presents a multimodal dataset from a 40-hour forced-desynchrony protocol to study circadian rhythms and their effects on physiology, ocular function, and behavior.

The self-renewing lymphoid-biased hematopoietic stem cells support long-term lymphopoiesis in mice

The paper identifies a self-renewing lymphoid-biased HSC subset in mice that maintains lymphopoiesis during aging and may serve as a backup source for immune function.

A developmentally scheduled inhibitory polarity circuit centers the stomatal pore

The paper identifies a polarity circuit in guard cells that determines stomatal pore position through MUS and OPL2 interactions, revealing a mechanism for coordinated cellular asymmetry.

The small ORF (smORF)-encoded polypeptide MIRINE promotes neuronal differentiation in vertebrate brain development

The paper identifies MIRINE, a small ORF-encoded polypeptide that promotes neuronal differentiation in vertebrate brain development by regulating the balance between proliferation and maturation.

Synthetic auxotrophy reveals metabolic regulation of plasma cell generation, affinity maturation, and cytokine receptor signaling

The paper shows that glutaminolysis and mitochondrial metabolism are conditionally crucial for B cell differentiation and cytokine signaling, revealing metabolic regulation of plasma cell generation and cytokine receptor signaling.

USP18-STAT2 axis enhances hepatic resilience under proteotoxic stress

This study identifies the USP18-STAT2 axis as a critical factor enhancing hepatic resilience under proteotoxic stress by modulating interferon signaling and ISG solubility.

High-light adaptation via ferredoxin-mediated tuning of the photosynthesis–photoprotection trade-off

Overexpression of Fd1 in tobacco plants adjusts the photosynthesis/photoprotection trade-off to enhance high-light adaptation.

Cytoplasmic recapping commences the translation of a micropeptide, MARS from MALAT1 after the removal of an inhibitory RNA G-quadruplex

This study shows that cytoplasmic recapping of MALAT1 produces the micropeptide MARS, which is regulated by RNA G-quadruplex structures and involved in oxidative stress response.

A domesticated prophage enzyme links bacterial metabolism, episymbiosis and phage fitness

The paper identifies a prophage-encoded enzyme that links bacterial metabolism, episymbiosis, and phage fitness by remodeling host structures and promoting symbiotic interactions.

Inter-strain diversity among coastal picocyanobacteria across salinity gradients

The paper examines how picocyanobacterial strains from different salinities adapt their growth and metabolism across varying salinity and light conditions.

Conserved RGF1 peptide signaling regulates root meristem development through ROS in Arabidopsis and rice

This study shows that RGF1 peptide signaling via ROS regulates root meristem development in Arabidopsis and rice, with conserved function across dicots and monocots.

Endosome motility controls light-responsive reproductive development and secondary metabolite production in Aspergillus

This study shows that endosome motility in Aspergillus species affects light-responsive development and secondary metabolite production.

CONSERVED LIFE HISTORY PHENOTYPES AMONG HISTORICALLY ISOLATED CLADES IN THE CHIRAL LIVEBEARER FISH OF LOWER CENTRAL AMERICA

The paper examines life history traits across four clades of the chiral livebearer fish Xenophallus umbratilis to assess conservation needs and adaptive evolution.

Cis-Regulatory Evolution of CCNB1IP1 Driving Gradual Increase of Cortical Size and Folding in primates

This study identifies CCNB1IP1 as a regulator of neocortex size and folding in primates, showing its expression increased alongside brain evolution.

A microbiota-derived protease links phage susceptibility to host epithelial responses

This study identifies a bacterial protease that influences phage susceptibility and links it to host epithelial responses in ulcerative colitis.

Protein phosphatase 2C domain contributes to the pathobiological function of adenylyl cyclase in Cryptococcus neoformans

The paper identifies the protein phosphatase 2C domain of adenylyl cyclase in Cryptococcus neoformans as essential for its pathobiological functions, affecting virulence and immune response.

Loss of restriction-modification methyltransferases drives persistence to fluoroquinolones in Pseudomonas aeruginosa

This study shows that loss of type I restriction-modification methyltransferases in Pseudomonas aeruginosa increases fluoroquinolone persistence through enhanced SOS response and slower growth.