A. Dimas

Comprehensive profiling of genomic invertons in defined gut microbial community reveals associations with intestinal colonization and surface adhesion

The paper develops a method to detect invertons in gut microbiome metagenomic data and finds associations between inverton dynamics and intestinal colonization and surface adhesion.

Gut microbiota gate host exposure to cholinesterase inhibitors from dietary Solanums

The paper investigates how gut microbiota modify steroidal alkaloids from Solanum plants, affecting host exposure and physiological effects.

Discovery and engineering of the antibody response against a prominent skin commensal

The paper identifies an antibody response against Staphylococcus epidermidis and shows how it can be engineered for therapeutic vaccination.

Engineered Skin Microbiome Reduces Mosquito Attraction to Mice

This study reduces mosquito attraction to mice by engineering their skin microbiome to lower lactic acid production, offering longer protection than DEET.

Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome

The paper investigates how strain dropouts in the gut microbiome affect community metabolism and host physiology, finding that functionally redundant strains can have significant impacts outside their niche.

Mapping the T cell repertoire to a complex gut bacterial community

The paper maps T cell responses to a complex gut bacterial community and identifies a conserved antigen recognized by multiple TCRs.

Eliciting a potent antitumor immune response by expressing tumor antigens in a skin commensal

This paper shows that expressing tumor antigens in skin commensal bacteria can elicit a potent antitumor immune response without causing autoimmunity.