Author

A. Eberhardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2

Frequent Co-Authors

J. Caramel· 3 shared M. Grimont· 3 shared S. Dalle· 3 shared C. Caux· 2 shared J. Valladeau-Guilemond· 2 shared M. Hubert· 2 shared M. Plaschka· 2 shared V. Benboubker· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

J. Caramel

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Spatial architecture of CD8+ T cells and DC subsets is critical for the response to immune checkpoint inhibitors in melanoma

E. Gobbini, M. Hubert, A.-C. Doffin, A. Eberhardt, L. Hermet, D. Li, P. Duplouye, S. Barrin, J. Berthet, V. Benboubker, M. Grimont, C. Sakref, J. Perrot, G. Tondeur, O. Harou, , J. Valladeau-Guilemond

This study examines the spatial organization of dendritic cell (DC) subsets and their interactions with CD8+ T cells in melanoma patients, finding that proximity between cDC1 and CD8+ T cells correlates with response to immune checkpoint inhibitors.

bioRxiv · Feb 6, 2024 · PreprintCancer Biology

A Unique Polyfunctional IL-33-responsive ST2⁺ NK cell State Potentiates Antitumor Immunity and Response to Immunotherapy

A. Eberhardt, E. Blanc, V. Picant, A. Voissiere, L. Revol-Bauz, T. Casini, V. Alcazer, D. Poujol, L. Tonon, R. Schneider, E. Picard, Y. Rocca, M. Ardin, F. Onodi, C. Degletagne, , N. Bendriss-Vermare

The paper identifies a unique ST2+ NK cell state that enhances antitumor immunity and response to immunotherapy through IL-33 and IL-12 signaling.

bioRxiv · Feb 14, 2023 · PreprintCancer Biology

ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions

S. Durand, Y. TANG, R. M. Pommier, V. Benboubker, M. Grimont, F. Boivin, L. Barbollat, E. Cumunel, F. Dupeuble, A. Eberhardt, M. Plaschka, S. Dalle, J. CARAMEL

This study identifies ZEB1 as a key transcriptional regulator driving melanoma cell state transitions by modulating lineage-specific programs.

bioRxiv · Feb 10, 2023Cancer Biology

An in vivo avian model of human melanoma to perform rapid and robust preclinical studies

L. Jarrosson, S. Dalle, C. Costechareyre, Y. Tang, M. Grimont, M. Plaschka, M. Lacourrege, R. Teinturier, M. Le Bouar, D. Maucort-Boulch, A. Eberhardt, V. Castellani, J. Caramel, C. Delloye-Bourgeois

This paper develops an avian xenograft model to rapidly study melanoma drug responses and resistance mechanisms in vivo.

bioRxiv · Oct 12, 2022 · PreprintCancer Biology

The Ocular Glymphatic Clearance System

X. Wang, N. Lou, A. Eberhardt, P. Kusk, Q. Xu, B. Forstera, S. Peng, Y. Yang, M. Shi, A. L. R. Xavier, A. Erturk, R. T. Libby, L. Chen, A. S. Thrane, M. Nedergaard

The paper identifies a novel glymphatic pathway in the optic nerve for clearing amyloid-beta from the vitreous, which is impaired in glaucoma.

bioRxiv · Dec 29, 2019 · PreprintPhysiology

Cancer cell CCR2 orchestrates suppression of the adaptive immune response

M. R. Fein, X. Y. He, A. S. Almeida, E. Bruzas, A. Pommier, R. Yan, A. Eberhardt, D. T. Fearon, L. Van Aelst, J. E. Wilkinson, C. O. dos Santos, M. Egeblad

This study shows that CCR2 in cancer cells suppresses immune response by reducing CD103+ dendritic cell recruitment and altering immune cell infiltration and activation.

bioRxiv · Dec 27, 2019Cancer Biology