A. Kane

Analog epigenetic memory revealed by targeted chromatin editing

This study reveals analog epigenetic memory through graded DNA methylation, showing its temporal stability and role in gene expression regulation.

Attenuation of the CpG Island Methylator Phenotype and lack of WNT signaling activation restrains Kras mutant intestinal neoplasia

This study compares Kras and Braf mutant intestinal neoplasia in mice, showing Kras mutations lead to less aggressive serrated lesions with reduced WNT signaling activation and attenuated DNA methylation changes compared to Braf mutations.

Soft selection affects introgression dynamics and the viability of populations experiencing intrusion of maladapted individuals

This study shows that soft selection influences introgression dynamics and population viability when maladapted individuals intrude into wild populations, depending on their competitiveness.

Patching Science - amending the literature through version control

The paper surveys academic dissatisfaction with current practices for amending published literature and proposes a version control system led by authors to improve scientific self-correction.

Mechanosensation Mediates Long-Range Spatial Decision-Making in an Aneural Organism

This paper shows that the aneural protist Physarum polycephalum uses mechanosensation to preferentially grow toward heavier, chemically inert masses, revealing a novel biomechanical decision-making mechanism.

APC Mutation marks an aggressive subtype of BRAF mutant colorectal cancers

This study identifies APC mutations as a marker of aggressive BRAF mutant colorectal cancers, associated with poor prognosis and enhanced tumor growth in mouse models.

Influence of plant genotype and soil on the wheat rhizosphere microbiome: Evidences for a core microbiome across eight African and European soils

The paper investigates the influence of wheat genotype and soil on the rhizosphere microbiome, identifying a core microbiome across diverse soils.

Development of a model estimating root length density from root impacts on a soil profile in pearl millet (Pennisetum glaucum (L.) R. Br). Application to measure root system response to water stress in field conditions

The paper develops a model to estimate root length density from root intersection densities in pearl millet, showing root reorientation under water stress.