Author

D. Ingber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Animal Behavior & Cognition· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:organoid / primary culture· 1 Assay:protein sequence· 1

Frequent Co-Authors

L. Si· 2 shared R. Prantil-Baun· 2 shared A. Graveline· 1 shared A. Herland· 1 shared A. Jiang· 1 shared A. Kane· 1 shared A. Minabutdinov· 1 shared A. Özkan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

L. Si

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

DNA origami vaccine (DoriVac) nanoparticles improve both humoral and cellular immune responses to infectious diseases

Y. Zeng, O. Young, Q. Xiong, L. Si, M. W. Ku, S. Bernier, H. Dembele, G. Isinelli, T. Gilboa, Z. Swank, S. H. Seok, A. Rajwar, A. Jiang, Y. Zhai, L. Williams, , W. Shih

This study demonstrates that DNA origami vaccine nanoparticles enhance both humoral and cellular immune responses against infectious diseases like SARS-CoV-2, HIV, and Ebola.

bioRxiv · Dec 29, 2023 · PreprintImmunology

Predicting drug concentrations in PDMS microfluidic organ chips

J. Grant, A. Özkan, C. Oh, G. Mahajan, R. Prantil-Baun, D. Ingber

This paper develops a simulation and experimental method to predict drug concentration profiles in PDMS microfluidic organ chips without prior knowledge of log P or diffusion rates.

bioRxiv · May 1, 2021Bioengineering

Mechanosensation Mediates Long-Range Spatial Decision-Making in an Aneural Organism

N. Murugan, D. Kaltman, H. Jin, M. Chien, R. Flores, C. Nguyen, D. Tuzoff, A. Minabutdinov, A. Kane, R. Novak, D. Ingber, M. Levin

This paper shows that the aneural protist Physarum polycephalum uses mechanosensation to preferentially grow toward heavier, chemically inert masses, revealing a novel biomechanical decision-making mechanism.

bioRxiv · Mar 20, 2020Animal Behavior & Cognition

Discovery of influenza drug resistance mutations and host therapeutic targets using a human airway chip

L. Si, R. Prantil-Baun, K. Benam, H. Bai, M. Rodas, M. Burt, D. Ingber

The paper uses a human airway chip to discover influenza drug resistance mutations and identify host therapeutic targets for antiviral drugs.

bioRxiv · Jun 27, 2019 · PreprintBioengineering

Liver-Chip: Reproducing Human and Cross-Species Toxicities

K.-J. Jang, M. Otieno, J. Ronxhi, H.-K. Lim, L. Ewart, K. Kodella, D. Petropolis, G. Kulkarni, J. Rubins, D. Conegliano, J. Nawroth, D. Simic, W. Lam, M. Singer, E. Barale, , G. Hamilton

The paper designs Liver-Chips for rat, dog, and human to replicate species-specific liver toxicities and predict human relevance.

bioRxiv · May 15, 2019 · PreprintPharmacology & Toxicology