Author

A. Leon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 2 Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:behavioral assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:synaptic & neural circuits· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

I. Guzman· 2 shared M. L. Avendano-Garrido· 2 shared P. Toledo· 2 shared A. Alfaro· 1 shared A. Kungl· 1 shared B. Gesslbauer· 1 shared C. A. Hernandez-Linares· 1 shared C. Farrell· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersAnimal Behavior & Cognition

I. Guzman

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2.

J. Hall, E. Hofmeister, H. Ip, S. Nashold, A. Leon, C. Malave, E. Falendysz, T. Rocke, M. Carossino, U. Balasuriya, S. Knowles

This study infects Mexican free-tailed bats with SARS-CoV-2 and finds they can become infected but do not show disease symptoms or transmit the virus.

bioRxiv · Jul 18, 2022Pathology

An Ecological Approach to the Effects of Water-Source Locations and Time-Based Schedules on Entropy and Spatio-Temporal Behavioral Features

V. Hernandez-Eslava, A. Leon, I. Guzman, F. Diaz, M. L. Avendano-Garrido, P. Toledo, C. A. Hernandez-Linares, I. Luna

This study examines how water delivery location and time-based schedules affect spatial behavior in rats, finding location-schedule interactions influence spatial organization.

bioRxiv · Jul 15, 2021 · PreprintAnimal Behavior & Cognition

Beyond single discrete responses: An integrative and multidimensional analysis of behavioral dynamics assisted by Machine Learning

A. Leon, V. Hernandez, J. Lopez, I. Guzman, V. Quintero, P. Toledo, M. L. Avendano-Garrido, C. Hernandez-Linares, E. Escamilla

This paper introduces a multidimensional analysis of behavioral dynamics using machine learning to integrate continuous spatial behavior with discrete responses, revealing previously overlooked aspects of behavior.

bioRxiv · Mar 17, 2021Animal Behavior & Cognition

Structural fuzziness of the RNA-organizing protein SERF1a determines a toxic gain-of-interaction

F. Falsone, H. Meyer, H. Dellago, C. Tam-Amersdorfer, D. Merle, R. Parlato, B. Gesslbauer, J. Almer, M. Gschwandtner, A. Leon, T. Franzmann, J. Grillari, A. Kungl, K. Zangger

This study identifies SERF1a as an RNA-organizing protein with structural fuzziness that enables toxic interactions with alpha-Synuclein, contributing to neurodegenerative disease mechanisms.

bioRxiv · Jul 24, 2019Biochemistry

MgO nanoparticles coated with Polyethylene Glycol as carrier for 2-Methoxyestradiol anticancer drug.

A. Alfaro, A. Leon, E. Guajardo, P. Reuquen, F. Torres, M. Mery, R. Segura, P. Zapata, p. orihuela

This paper develops MgO nanoparticles coated with PEG as a drug delivery system for 2-Methoxyestradiol, showing high drug loading and sustained release, and reduced prostate cancer cell viability.

bioRxiv · Mar 25, 2019Cancer Biology

Multi-plane Imaging of Neural Activity From the Mammalian Brain Using a Fast-switching Liquid Crystal Spatial Light Modulator

R. Liu, N. Ball, J. Brockill, L. Kuan, D. Millman, C. White, A. Leon, D. Williams, S. Nishiwaki, S. de Vries, J. Larkin, D. Sullivan, C. Slaughterbeck, C. Farrell, P. Saggau

The paper introduces a new two-photon microscope using a liquid crystal spatial light modulator to record neural activity in awake mice, finding heterogeneous responses in excitatory neurons across cortical layers.

bioRxiv · Dec 30, 2018Bioengineering