Prediction and validation of host cleavage targets of SARS-CoV-2 3C like protease
N. Yucel, S. Marchiano, E. Tchelepi, Q. McAfee, N. Nimmagadda, A. Ren, S. Shi, C. E. Murry, Z. Arany
This study predicts and validates host cleavage targets of SARS-CoV-2 3CL protease using bioinformatics and experimental methods, identifying new targets like Obscurin and linking them to cardiac dysfunction in COVID-19.
bioRxiv · Jan 17, 2022 · PreprintMicrobiology