B. K. Das

Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton

This study shows that TFR1-mediated iron uptake in osteoclasts affects mitochondrial function and cytoskeleton, leading to increased bone mass in female mice.

Comparative kinetic analysis of ascorbate (Vitamin-C) recycling dehydroascorbate reductases from plant and human.

This study compares the kinetic properties of plant and human DHAR enzymes, revealing differences in turnover rates and oxidation susceptibility that correlate with their cellular environments.

Dual avatars of E. coli grxB encoded Glutaredoxin 2 perform ascorbate recycling and ion channel activities

This study identifies two functional roles of EcGrx2: ascorbate recycling and ion channel activity, revealing its role in antioxidant defense and membrane integration in E. coli.

The evolution of regulatory elements in the emerging promoter variant strains of HIV-1

The paper identifies nine promoter-variant strains of HIV-1C in Indian patients, showing genetic diversity in transcription factor binding sites that may affect viral latency and reservoir characteristics.

Plasma neutralizing antibodies in an infant with interclade HIV-1 superinfection preferentially neutralize superinfecting HIV-1 strains

This study examines nAb responses in an infant with interclade HIV-1 superinfection, finding that neutralizing antibodies primarily target the superinfecting strain and depend on glycans.

A rare mutation in an infant derived HIV-1 envelope glycoprotein alters interprotomer stability and susceptibility to broadly neutralizing antibodies targeting the trimer apex

The paper identifies a rare L184F mutation in HIV-1 Env that destabilizes the trimer apex, leading to escape from broadly neutralizing antibodies targeting the V2 apex.

Broadly neutralizing plasma antibodies effective against diverse autologous circulating viruses in infants with multivariant HIV-1 infection.

The paper identifies viral factors associated with early broadly neutralizing antibody (bnAb) responses in HIV-1-infected infants and suggests implications for polyvalent vaccination strategies.

Viral characteristics associated with sustenance of elite neutralizing activity in chronically HIV-1C infected monozygotic pediatric twins

This study compares viral characteristics in two HIV-1C infected monozygotic twins with differing elite neutralizing antibody profiles, identifying viral mutations associated with neutralization resistance and susceptibility.