S. Mohan

The Radiogenomic and Spatiogenomic Landscapes of Glioblastoma, and Their Relationship to Oncogenic Drivers

This study identifies imaging and spatial biomarkers in glioblastoma that correlate with molecular features and oncogenic drivers using machine learning on MRI data.

Differences in pathways contributing to thyroid hormone effects on postnatal cartilage calcification versus secondary ossification center development

This study investigates how thyroid hormone affects cartilage calcification in the proximal femur versus secondary ossification center development in the distal femur, identifying distinct molecular pathways.

Low antigen abundance limits efficient T-cell recognition of highly conserved regions of SARS-CoV-2

The paper identifies conserved T-cell epitopes in SARS-CoV-2 and finds that immune responses against them are subdominant due to low antigen abundance.

Hexapeptides from mammalian inhibitory hormone hunt activate and inactivate nematode reproduction

The paper identifies hexapeptides that upregulate and downregulate nematode reproduction and show bioactivity in mammalian systems.

Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton

This study shows that TFR1-mediated iron uptake in osteoclasts affects mitochondrial function and cytoskeleton, leading to increased bone mass in female mice.

Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infecting H10N8 Influenza A virus

This paper identifies two drug-resistant mutations in H10N8 influenza virus and explains their structural mechanisms using crystallography, showing differences in resistance to neuraminidase inhibitors.

Maternal effects influence temperature-dependent offspring survival in Drosophila melanogaster

The paper shows maternal effects improve offspring survival when maternal and offspring temperatures match in Drosophila melanogaster, but have limited impact on adult traits.