B. Lam

Quantitative imaging of gene therapy delivery vehicles using CEST-NMR/MRI

This study uses CEST-NMR/MRI to quantify AAV vector delivery by measuring CEST contrast from viral capsids, showing strong correlations with capsid density and viral titer.

Sensitivity of diffusion-tensor and correlated diffusion imaging to white-matter microstructural abnormalities: application in COVID-19

This study compares diffusion MRI methods to detect white-matter changes in COVID-19 patients, finding correlated diffusion imaging is most sensitive to microstructural abnormalities.

Disease diagnostics using machine learning of immune receptors

The paper develops Mal-ID, a machine learning framework using immune receptor data to diagnose diseases, detecting infections, autoimmune disorders, and vaccine responses.

High Throughput Screening at the Membrane Interface Reveals New Inhibitors of Amyloid-β

This study identifies 5 small molecules that inhibit amyloid-β aggregation at the cell-membrane interface, which is relevant for Alzheimer's disease.

Comparison of human and murine enteroendocrine cells by transcriptomic and peptidomic profiling

This study compares human and mouse enteroendocrine cells using transcriptomic and peptidomic profiling to assess mouse as a model for human enteroendocrine function.

Type-I interferons inhibit interleukin-10 signaling and favor type 1 diabetes development in NOD mice

This study shows that type-I interferons inhibit IL-10 signaling in T cells, promoting type 1 diabetes in NOD mice by altering T cell responses and spatial localization.