BLOC1S1 control of vacuolar organelle fidelity modulates TH2 cell immunity and allergy susceptibility.
R. Sharma, K. Wu, K. Han, A. C. Russo, P. K. Dagur, C. A. Combs, M. N. Sack
This study shows that BLOC1S1 depletion disrupts mitochondrial integrity, leading to TH2 cell immunity and allergy susceptibility via STING-NF-κB signaling.
bioRxiv · Mar 21, 2024 · PreprintImmunology