Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
S. Park, S. Choi, A. A. Shimpi, L. A. Estroff, C. Fischbach, M. J. Paszek
This study shows that collagen mineralization increases NK cell resistance in breast cancer by thickening the tumor cell glycocalyx through enhanced sialylation.
bioRxiv · Jan 20, 2024Cancer Biology
S. Choi, M. A. Whitman, A. A. Shimpi, N. D. Sempertegui, A. Chiou, J. E. Druso, A. Verma, S. C. Lux, Z. Cheng, M. Paszek, O. Elemento, L. A. Estroff, C. Fischbach
The paper shows that mineralization in bone matrix models inhibits tumor cell proliferation and induces a stem-like phenotype, contradicting the assumption that rigidity promotes metastasis.
bioRxiv · Jun 29, 2022 · PreprintBioengineering
A. A. Shimpi, M. L. Tan, M. Vilkhovoy, D. Dai, L. M. Roberts, J. C.-H. Kuo, L. Huang, J. Varner, M. J. Paszek, C. Fischbach
This study investigates how hyaluronic acid biosynthesis affects metabolic regulation of tumor invasion in breast cancer cells using integrated experimental and computational approaches.
bioRxiv · Jun 8, 2022Cancer Biology
S. Park, M. J. Colville, C. R. Shurer, L.-T. Huang, J. C.-H. Kuo, J. H. Paek, M. C. Goudge, J. Su, M. P. DeLisa, J. Lammerding, W. R. Zipfel, C. Fischbach, H. L. Reesink, M. J. Paszek
This study investigates how glycocalyx thickness, influenced by mucin properties, affects NK cell-mediated cytotoxicity and suggests strategies to enhance cancer immunotherapy.
bioRxiv · Jan 28, 2022 · PreprintBiophysics
A. Latifkar, F. Wang, J. J. Mullmann, I. R. Fernandez, L. Ling, C. Fischbach, R. S. Weiss, H. Lin, R. A. Cerione, M. A. Antonyak
The paper shows that IGF2BP2 degradation of ATP6V1A transcript, driven by SIRT1 down-regulation and acetylation, impairs lysosomal function and promotes cancer progression.
bioRxiv · Apr 1, 2021Cell Biology