Author

C. Moon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 8 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Research Focus:drug response / drug discovery· 5 Organism:mouse· 4 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1 Assay:metagenomics· 1

Frequent Co-Authors

R. O. Williams· 8 shared S. Sahakijpijarn· 7 shared D. J. Christensen· 5 shared Z. Cui· 5 shared H. Xu· 4 shared J. J. Koleng· 3 shared H. M. Dao· 2 shared Z. N. Warnken· 2 shared

Activity by Year

2020-2022 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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8 shared papersPharmacology & Toxicology

R. O. Williams

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Patterns and determinants of the global herbivorous mycobiome

C. Meili, A. L. Jones, A. X. Arreola, j. Habel, C. J. Pratt, R. A. Hanafy, Y. Wang, A. S. Yassin, M. A. TagElDein, C. Moon, P. H. Janssen, M. Shrestha, P. Rajbhandari, M. Nagler, J. M. Vinzelj, , M. S. Elshahed

The paper analyzes AGF diversity across 661 fecal samples from 34 herbivorous species, identifying 56 novel genera and showing that both stochastic and deterministic processes shape AGF communities, with hindgut fermenters having stronger host-specific associations.

bioRxiv · Nov 21, 2022Microbiology

Aerosolizable plasmid DNA dry powders engineered by thin-film freezing

H. Xu, C. Moon, S. Sahakijpijarn, H. M. Dao, R. F. Alzhrani, J.-l. Wang, R. O. Williams, Z. Cui

This study tests thin-film freezing to create aerosolizable plasmid DNA dry powders for pulmonary delivery, finding good aerosol performance and preserved pDNA integrity.

bioRxiv · Oct 3, 2022Pharmacology & Toxicology

Peroxiredoxin 5 regulates osteogenic differentiation via interaction with hnRNPK during bone regeneration

E. Cho, X. Che, M. J. Ang, S. Cheon, J. Lee, K. Kim, C. H. Lee, S.-Y. Lee, H.-Y. Yang, C. Moon, C. Park, J.-Y. Choi, T.-H. Lee

This study identifies Prdx5's role in bone regeneration by regulating osteoblast differentiation through interaction with hnRNPK, impacting osteocalcin expression and osteoclast activity.

bioRxiv · Jun 9, 2022Cell Biology

Degradation of lactoferrin caused by droplet atomization process via two fluid nozzle: The detrimental effect of air water interfaces

H. M. Dao, S. Sahakijpijarn, R. R. Chrostowski, C. Moon, F. Mangolini, Z. Cui, R. O. Williams

This study investigates how the droplet atomization process in spray freeze-drying affects lactoferrin stability, finding that high air-water interfaces cause conformational changes and aggregation.

bioRxiv · Dec 6, 2021 · PreprintPharmacology & Toxicology

Dry Powders for Inhalation Containing Monoclonal Antibodies Made by Thin-Film Freeze-Drying

S. Hufnagel, H. Xu, S. Sahakijpijarn, C. Moon, L. Q. M. Chow, R. O. Williams, Z. Cui

This paper demonstrates that thin-film freeze-drying produces stable aerosolizable dry powders of monoclonal antibodies for pulmonary delivery.

bioRxiv · Oct 29, 2021Pharmacology & Toxicology

Formulation of Dry Powders of Vaccines Containing MF59 or AddaVax by Thin-Film Freeze-Drying

K. AboulFotouh, N. Uno, H. Xu, C. Moon, S. Sahakijpijarn, D. J. Christensen, G. J. Davenport, C. Cano, T. M. Ross, R. O. Williams, Z. Cui

This study demonstrates that thin-film freeze-drying can convert MF59 or AddaVax-adjuvanted vaccines into dry powders while preserving immunogenicity and stability.

bioRxiv · Oct 21, 2021 · PreprintPharmacology & Toxicology

AUG-3387, a Human-Derived Monoclonal Antibody Neutralizes SARS-CoV-2 Variants and Reduces Viral Load from Therapeutic Treatment of Hamsters In Vivo

C. J. Emig, M. A. Mena, S. J. Henry, A. Vitug, C. J. Ventura, D. Fox, X. H. Nguyenla, H. Xu, C. Moon, S. Sahakijjpijarn, P. J. Kuehl, D. Revelli, Z. Cui, R. O. Williams, D. J. Christensen

AUG-3387, a human monoclonal antibody, neutralizes SARS-CoV-2 variants and reduces viral load in hamsters when administered as a dry powder inhaler formulation.

bioRxiv · Oct 12, 2021 · PreprintPharmacology & Toxicology

Niclosamide Inhalation Powder Made by Thin-Film Freezing: Pharmacokinetic and Toxicology Studies in Rats and Hamsters

M. O. Jara, Z. N. Warnken, S. Sahakijpijarn, C. Moon, E. Y. Maier, D. J. Christensen, J. J. Koleng, J. I. Peters, S. D. Hackman, R. O. Williams

This paper develops a niclosamide inhalation powder using thin-film freezing and tests its pharmacokinetics and toxicity in rats and hamsters for COVID-19 treatment.

bioRxiv · Jan 26, 2021 · PreprintPharmacology & Toxicology

In Vivo Pharmacokinetic Study of Remdesivir Dry Powder for Inhalation in Hamsters

s. sahakijpijarn, C. Moon, Z. N. Warnken, E. Maier, J. E. DeVore, D. J. Christensen, J. J. Koleng, R. O. Williams

This study evaluates the pharmacokinetics of remdesivir dry powder for inhalation in hamsters, showing higher drug levels and suggesting a twice-daily dosing regimen.

bioRxiv · Dec 22, 2020Pharmacology & Toxicology

Development of Remdesivir as a Dry Powder for Inhalation by Thin Film Freezing

S. Sahakijpijarn, C. Moon, J. J. Koleng, D. J. Christensen, R. O. Williams

This paper develops a dry powder formulation of remdesivir for inhalation using thin film freezing, showing improved aerosol performance and lung delivery.

bioRxiv · Jul 26, 2020Pharmacology & Toxicology