Author

C. Pape

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 3 Assay:imaging· 3 Research Focus:clustering· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:differential expression· 1

Frequent Co-Authors

A. Kreshuk· 4 shared A. Wolny· 2 shared C. J. Neufeldt· 2 shared C. Tischer· 2 shared F. A. Hamprecht· 2 shared L. Cerrone· 2 shared M. Cortese· 2 shared R. Bartenschlager· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersCell Biology

A. Kreshuk

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

CebraEM: A practical workflow to segmentcellular organelles in volume SEM datasetsusing a transferable CNN-based membraneprediction

J. Hennies, J. M. S. Lleti, C. Pape, S. Bekbayev, V. Gross, A. Kreshuk, Y. Schwab

CebraEM provides a workflow for segmenting cellular organelles in volume SEM datasets using a transferable CNN-based membrane prediction, achieving state-of-the-art results with minimal post-processing.

bioRxiv · Apr 6, 2023 · PreprintCell Biology

LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome

A. V. Busley, O. Gutierrez-Gutierrez, E. Hammer, F. Koitka, A. Mirzaiebadizi, M. Steinegger, C. Pape, L. Boehmer, H. Schroeder, M. Kleinsorge, M. Engler, I. C. Cirstea, L. Gremer, D. Willbold, J. Altmueller, , L. Cyganek

This study identifies a novel LZTR1 variant causing cardiac hypertrophy by altering protein polymerization and ubiquitin ligase function, showing genetic correction can rescue the phenotype.

bioRxiv · Jan 10, 2023Cell Biology

Microscopy-based assay for semi-quantitative detection of SARS-CoV-2 specific antibodies in human sera

C. Pape, R. Remme, A. Wolny, S. Olberg, S. Wolf, L. Cerrone, M. Cortese, S. Klaus, B. Lucic, S. Ullrich, M. Anders-Össwein, S. Wolf, C. Berati, C. J. Neufeldt, M. Ganter, , V. Laketa

The paper develops a semi-quantitative microscopy-based assay to detect SARS-CoV-2 specific antibodies in human sera, providing a sensitive and specific method for serological analysis.

BioEssays · Dec 30, 2020Peer-reviewedMicrobiology

A versatile reporter system to monitor virus infected cells and its application to dengue virus and SARS-CoV-2

F. Pahmeier, C. J. Neufeldt, B. Cerikan, V. Prasad, C. Pape, V. Laketa, A. Ruggieri, R. Bartenschlager, M. Cortese

This paper introduces a versatile reporter system that detects virus-infected cells by using protease activity and applies it to dengue virus and SARS-CoV-2.

bioRxiv · Aug 31, 2020Microbiology

Whole-body integration of gene expression and single-cell morphology

H. M. Vergara, C. Pape, K. Meechan, V. Zinchenko, C. Genoud, A. A. Wanner, B. Titze, R. Templin, P. Y. Bertucci, O. Simakov, P. Machado, E. L. Savage, Y. Schwab, R. W. Friedrich, A. Kreshuk, , D. Arendt

The paper integrates gene expression and single-cell morphology in Platynereis dumerilii to identify spatially coherent cell groups defined by transcription factors.

bioRxiv · Feb 26, 2020Cell Biology

Accurate And Versatile 3D Segmentation Of Plant Tissues At Cellular Resolution

A. Wolny, L. Cerrone, A. Vijayan, R. Tofanelli, A. V. Barro, M. Louveaux, C. Wenzl, S. Steigleder, C. Pape, A. Bailoni, S. Duran-Nebreda, G. Bassel, J. U. Lohmann, F. A. Hamprecht, K. Schneitz, , A. Kreshuk

PlantSeg provides a deep learning-based pipeline for accurate 3D segmentation of plant tissues into individual cells across various developmental contexts.

bioRxiv · Jan 17, 2020Plant Biology