Author

C.-F. Hung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Bennett· 1 shared A. Kotwal· 1 shared A. Skaist· 1 shared A. Wu· 1 shared B.-Y. Huang· 1 shared C.-H. Tsai· 1 shared C.-L. Tsai· 1 shared C.-P. Mao· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Bennett

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Simultaneous CRISPR-Cas9-induced double strand breaks are lethal in models of pancreatic cancer

S. S. K. Teh, A. Kotwal, A. Bennett, E. Halper-Stromberg, L. Morsberger, S. Zamani, Y. Shi, A. Skaist, Q. Zhu, K. Bowland, H. Liang, R. H. Hruban, C.-F. Hung, R. A. Anders, N. J. Roberts, , J. R. Eshleman

This study shows CRISPR-Cas9-induced DNA double-strand breaks are more cytotoxic to pancreatic cancer cells than radiation-induced breaks, with significant tumor growth inhibition and chromosomal instability.

bioRxiv · Apr 3, 2023Cancer Biology

Protein detection in blood with single-molecule imaging

C.-P. Mao, S.-C. Wang, Y.-P. Su, S.-H. Tseng, L. He, A. Wu, R. Roden, J. Xiao, C.-F. Hung

This paper introduces SMAC, a single-molecule imaging technique that detects disease-specific proteins in blood samples at subfemtomolar concentrations.

bioRxiv · May 19, 2021Biophysics

Inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 main protease by tafenoquine in vitro

Y. Chen, W.-H. Yang, L.-M. Huang, Y.-C. Wang, C.-S. Yang, Y.-L. Liu, M.-H. Hou, C.-L. Tsai, Y.-Z. Chou, B.-Y. Huang, C.-F. Hung, Y.-L. Hung, J.-S. Chen, Y.-P. Chiang, D.-Y. Cho, , M.-C. Hung

This study identifies tafenoquine as an inhibitor of SARS-CoV-2 main protease, showing it reduces protease activity and inhibits viral infection in vitro.

bioRxiv · Aug 14, 2020 · PreprintBiochemistry

Antibiotic treatment shapes antigen presentation during chronic TB infection, offering novel targets for therapeutic vaccination

Y.-M. Chuang, N. K. Dutta, M. L. Pinn, C.-F. Hung, P. C. Karakousis

This study shows that antibiotic treatment alters antigen presentation during TB, and therapeutic vaccination targeting RelMtb enhances isoniazid efficacy against Mtb persisters.

bioRxiv · May 15, 2019Microbiology